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3-Hydroxypropionate bicycle
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<StructureSection load='' size='350' side='right' scene='49/492046/Cv/1' caption='E. coli Acetyl-CoA carboxylase biotinyl domain complex with biotin (PDB code [[1bdo]]) '> | <StructureSection load='' size='350' side='right' scene='49/492046/Cv/1' caption='E. coli Acetyl-CoA carboxylase biotinyl domain complex with biotin (PDB code [[1bdo]]) '> | ||
| - | The 3-Hydroxypropionate bicycle, also known as the 3-Hydroxypropionate pathway, is a process that allows some bacteria to generate 3-Hydroxypropionate utilizing carbon dioxide. In this pathway CO2 is fixed (''i.e.'' incorporated) by the action of two enzymes, [[acetyl-CoA carboxylase]] and propionyl-CoA carboxylase. | + | The 3-Hydroxypropionate bicycle, also known as the 3-Hydroxypropionate pathway, is a process that allows some bacteria to generate 3-Hydroxypropionate utilizing carbon dioxide. In this pathway CO2 is fixed (''i.e.'' incorporated) by the action of two enzymes, [[acetyl-CoA carboxylase]] and [[propionyl-CoA carboxylase]]. See also [[Carbon Fixation]]. |
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| + | These enzymes generate <scene name='49/492046/Cv/7'>malonyl-CoA</scene> and <scene name='95/950327/Cv/1'>(S)-methylmalonyl-CoA</scene>, respectively. Malonyl-CoA, in a series of reactions is further split into <scene name='43/430893/Cv/2'>acetyl-CoA</scene> and <scene name='93/939250/Cv/1'>glyoxylate</scene>. Glyoxylate is incorporated into beta-methylmalyl-CoA which is then split, again through a series of reactions to release pyruvate as well as acetate, which is used to replenish the cycle. | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
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