9b0l
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of Acanthamoeba polyphaga mimivirus Fanzor2 ternary complex== | |
| + | <StructureSection load='9b0l' size='340' side='right'caption='[[9b0l]], [[Resolution|resolution]] 2.99Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[9b0l]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthamoeba_polyphaga_mimivirus Acanthamoeba polyphaga mimivirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9B0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9B0L FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.99Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9b0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9b0l OCA], [https://pdbe.org/9b0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9b0l RCSB], [https://www.ebi.ac.uk/pdbsum/9b0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9b0l ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/YL079_MIMIV YL079_MIMIV] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | RNA-guided endonucleases, once thought to be exclusive to prokaryotes, have been recently identified in eukaryotes and are called Fanzors. They are classified into two clades, Fanzor1 and Fanzor2. Here we present the cryo-electron microscopy structure of Acanthamoeba polyphaga mimivirus Fanzor2, revealing its omegaRNA architecture, active site and features involved in transposon-adjacent motif recognition. A comparison to Fanzor1 and TnpB structures highlights divergent evolutionary paths, advancing our understanding of RNA-guided endonucleases. | ||
| - | + | , PMID:39354233<ref>PMID:39354233</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 9b0l" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Acanthamoeba polyphaga mimivirus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kalathur RC]] | ||
| + | [[Category: Kellogg EH]] | ||
| + | [[Category: Qayyum MZ]] | ||
| + | [[Category: Schargel RD]] | ||
| + | [[Category: Tanwar AS]] | ||
Current revision
Cryo-EM structure of Acanthamoeba polyphaga mimivirus Fanzor2 ternary complex
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