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2z1z

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{{Seed}}
 
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[[Image:2z1z.png|left|200px]]
 
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<!--
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==Crystal structure of LL-Diaminopimelate Aminotransferase from Arabidopsis thaliana complexed with L-malate ion==
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The line below this paragraph, containing "STRUCTURE_2z1z", creates the "Structure Box" on the page.
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<StructureSection load='2z1z' size='340' side='right'caption='[[2z1z]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2z1z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z1Z FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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{{STRUCTURE_2z1z| PDB=2z1z | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z1z OCA], [https://pdbe.org/2z1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z1z RCSB], [https://www.ebi.ac.uk/pdbsum/2z1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z1z ProSAT]</span></td></tr>
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</table>
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===Crystal structure of LL-Diaminopimelate Aminotransferase from Arabidopsis thaliana complexed with L-malate ion===
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== Function ==
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[https://www.uniprot.org/uniprot/DAPAT_ARATH DAPAT_ARATH] Required for lysine biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli. Not active with meso-diaminopimelate, lysine or ornithine as substrates.<ref>PMID:16361515</ref> <ref>PMID:21435399</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_17583737}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17583737 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z1/2z1z_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17583737}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2Z1Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1Z OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z1z ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana: a recently discovered enzyme in the biosynthesis of L-lysine by plants and Chlamydia., Watanabe N, Cherney MM, van Belkum MJ, Marcus SL, Flegel MD, Clay MD, Deyholos MK, Vederas JC, James MN, J Mol Biol. 2007 Aug 17;371(3):685-702. Epub 2007 May 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17583737 17583737]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: LL-diaminopimelate aminotransferase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Cherney MM]]
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[[Category: Belkum, M J.van.]]
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[[Category: Clay MD]]
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[[Category: Cherney, M M.]]
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[[Category: Deyholos MK]]
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[[Category: Clay, M D.]]
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[[Category: Flegel MD]]
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[[Category: Deyholos, M K.]]
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[[Category: James MNG]]
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[[Category: Flegel, M D.]]
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[[Category: Marcus SL]]
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[[Category: James, M N.G.]]
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[[Category: Vederas JC]]
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[[Category: Marcus, S L.]]
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[[Category: Watanabe N]]
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[[Category: Vederas, J C.]]
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[[Category: Van Belkum MJ]]
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[[Category: Watanabe, N.]]
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[[Category: Arabidopsis thaliana]]
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[[Category: Ll-dap]]
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[[Category: Ll-dap-at]]
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[[Category: Ll-diaminopimelate aminotransferase]]
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[[Category: Lysine biosynthesis]]
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[[Category: Plp]]
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[[Category: Thdpa]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:55:55 2008''
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Current revision

Crystal structure of LL-Diaminopimelate Aminotransferase from Arabidopsis thaliana complexed with L-malate ion

PDB ID 2z1z

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