3e59
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the PvcA (PA2254) protein from Pseudomonas aeruginosa== | |
| - | + | <StructureSection load='3e59' size='340' side='right'caption='[[3e59]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3e59]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E59 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E59 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | '' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e59 OCA], [https://pdbe.org/3e59 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e59 RCSB], [https://www.ebi.ac.uk/pdbsum/3e59 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e59 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PVCA_PSEAE PVCA_PSEAE] Involved in the biosynthesis of paerucumarin, a cyclized isocyano derivative of tyrosine (PubMed:18689486, PubMed:18824174). Responsible for the synthesis of the isonitrile group on tyrosine using the C2 of ribulose 5-phosphate as the source of the carbon atom (Probable).<ref>PMID:18689486</ref> <ref>PMID:18824174</ref> <ref>PMID:18824174</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e5/3e59_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e59 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas aeruginosa]] | ||
| + | [[Category: Drake EJ]] | ||
| + | [[Category: Gulick AM]] | ||
Current revision
Crystal structure of the PvcA (PA2254) protein from Pseudomonas aeruginosa
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