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3e59

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{{Seed}}
 
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[[Image:3e59.jpg|left|200px]]
 
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==Crystal structure of the PvcA (PA2254) protein from Pseudomonas aeruginosa==
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The line below this paragraph, containing "STRUCTURE_3e59", creates the "Structure Box" on the page.
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<StructureSection load='3e59' size='340' side='right'caption='[[3e59]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3e59]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E59 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E59 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_3e59| PDB=3e59 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e59 OCA], [https://pdbe.org/3e59 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e59 RCSB], [https://www.ebi.ac.uk/pdbsum/3e59 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e59 ProSAT]</span></td></tr>
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</table>
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===Crystal structure of the PvcA (PA2254) protein from Pseudomonas aeruginosa===
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== Function ==
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[https://www.uniprot.org/uniprot/PVCA_PSEAE PVCA_PSEAE] Involved in the biosynthesis of paerucumarin, a cyclized isocyano derivative of tyrosine (PubMed:18689486, PubMed:18824174). Responsible for the synthesis of the isonitrile group on tyrosine using the C2 of ribulose 5-phosphate as the source of the carbon atom (Probable).<ref>PMID:18689486</ref> <ref>PMID:18824174</ref> <ref>PMID:18824174</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18824174 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e5/3e59_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18824174}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3E59 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E59 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e59 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Three-dimensional Structures of Pseudomonas aeruginosa PvcA and PvcB, Two Proteins Involved in the Synthesis of 2-Isocyano-6,7-dihydroxycoumarin., Drake EJ, Gulick AM, J Mol Biol. 2008 Sep 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18824174 18824174]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Single protein]]
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[[Category: Drake EJ]]
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[[Category: Drake, E J.]]
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[[Category: Gulick AM]]
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[[Category: Gulick, A M.]]
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[[Category: 2-isocyano-6]]
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[[Category: 7-dihydroxycoumarin]]
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[[Category: Isonitrile]]
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[[Category: Paerucumarin]]
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[[Category: Pvca]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 15 15:58:13 2008''
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Current revision

Crystal structure of the PvcA (PA2254) protein from Pseudomonas aeruginosa

PDB ID 3e59

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