This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.

Template:STRUCTURE 3dxc

From Proteopedia

(Difference between revisions)

Jump to: navigation, search

Current revision

3dxc, resolution 2.10Å ()

Gene:

APBB1, FE65, RIR (Homo sapiens), APP, A4, AD1 (Homo sapiens)

Related:

3dxd, 3dxe

Structural annotation:
Resources:	InterPro : Ipr001202, Ipr006020, Ipr011993, Ipr002223, Ipr008154, Ipr008155, Ipr011178, Ipr013803, Ipr015849 Pfam : PF00640 UniProt : O00213, P05067

Functional annotation:
Cellular component:	nucleus lamellipodium synapse growth cone extracellular region integral to membrane integral to plasma membrane platelet alpha granule lumen coated pit cell surface membrane
Biological process:	signal transduction regulation of transcription negative regulation of cell growth axonogenesis cell cycle arrest negative regulation of thymidylate synthase biosynthetic process negative regulation of S phase of mitotic cell cycle cell adhesion apoptosis endocytosis cellular copper ion homeostasis Notch signaling pathway neuromuscular process
Molecular function:	beta-amyloid binding transcription factor binding protein binding heparin binding endopeptidase inhibitor activity metal ion binding binding identical protein binding zinc ion binding copper ion binding acetylcholine receptor binding iron ion binding serine-type endopeptidase inhibitor activity

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Caveats,

Explanation,
Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_3dxc"

@@ Line 1: / Line 1: @@
-{{StructureD
+{{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|3dxc, resolution 2.10&Aring; (<scene name='initialview01'>default scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[3dxc]], [[Resolution|resolution]] 2.10&Aring; (<scene name='initialview01'>default scene</scene>)}}}
 |GENE= APBB1, FE65, RIR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), APP, A4, AD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
 |RELATEDENTRY=[[3dxd|3dxd]], [[3dxe|3dxe]]
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dxc OCA], [http://www.ebi.ac.uk/pdbsum/3dxc PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3dxc RCSB]</span>
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dxc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dxc RCSB], [http://www.ebi.ac.uk/pdbsum/3dxc PDBsum]</span>
 |FUNCTION={{GO|id=GO:0001540 | text = beta-amyloid binding}}{{GO|id=GO:0008134 | text = transcription factor binding}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0008201 | text = heparin binding}}{{GO|id=GO:0004866 | text = endopeptidase inhibitor activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0005488 | text = binding}}{{GO|id=GO:0042802 | text = identical protein binding}}{{GO|id=GO:0008270 | text = zinc ion binding}}{{GO|id=GO:0005507 | text = copper ion binding}}{{GO|id=GO:0033130 | text = acetylcholine receptor binding}}{{GO|id=GO:0005506 | text = iron ion binding}}{{GO|id=GO:0004867 | text = serine-type endopeptidase inhibitor activity}}
 |PROCESS={{GO|id=GO:0007165 | text = signal transduction}}{{GO|id=GO:0045449 | text = regulation of transcription}}{{GO|id=GO:0030308 | text = negative regulation of cell growth}}{{GO|id=GO:0007409 | text = axonogenesis}}{{GO|id=GO:0007050 | text = cell cycle arrest}}{{GO|id=GO:0050760 | text = negative regulation of thymidylate synthase biosynthetic process}}{{GO|id=GO:0045749 | text = negative regulation of S phase of mitotic cell cycle}}{{GO|id=GO:0007155 | text = cell adhesion}}{{GO|id=GO:0006915 | text = apoptosis}}{{GO|id=GO:0006897 | text = endocytosis}}{{GO|id=GO:0006878 | text = cellular copper ion homeostasis}}{{GO|id=GO:0007219 | text = Notch signaling pathway}}{{GO|id=GO:0050905 | text = neuromuscular process}}
 |COMPONENT={{GO|id=GO:0005634 | text = nucleus}}{{GO|id=GO:0030027 | text = lamellipodium}}{{GO|id=GO:0045202 | text = synapse}}{{GO|id=GO:0030426 | text = growth cone}}{{GO|id=GO:0005576 | text = extracellular region}}{{GO|id=GO:0016021 | text = integral to membrane}}{{GO|id=GO:0005887 | text = integral to plasma membrane}}{{GO|id=GO:0031093 | text = platelet alpha granule lumen}}{{GO|id=GO:0005905 | text = coated pit}}{{GO|id=GO:0009986 | text = cell surface}}{{GO|id=GO:0016020 | text = membrane}}
 |SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001202 Ipr001202], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006020 Ipr006020], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011993 Ipr011993], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002223 Ipr002223], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008154 Ipr008154], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008155 Ipr008155], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011178 Ipr011178], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013803 Ipr013803], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR015849 Ipr015849]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00640 PF00640]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?O00213 O00213], [http://ca.expasy.org/cgi-bin/niceprot.pl?P05067 P05067]</span>
+|uPDB=3DXC|CONSURF={{!}}-
+{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
+{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
+{{!}} '''Toggle Conservation Colors:'''
+{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
+Rows = identical sequences:
+<jmol>
+<jmolButton>
+<script></script>
+<text>A [x]</text>
+<name>jmb_3dxc_A</name>
+<title>toggle chain A</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>C [x]</text>
+<name>jmb_3dxc_C</name>
+<title>toggle chain C</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>B [x]</text>
+<name>jmb_3dxc_B</name>
+<title>toggle chain B</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>D [x]</text>
+<name>jmb_3dxc_D</name>
+<title>toggle chain D</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
 }}

Template:STRUCTURE 3dxc

From Proteopedia

Current revision

Proteopedia Page Contributors and Editors (what is this?)

Views

Personal tools

Navigation

Search

Toolbox