3c7t

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{{Seed}}
 
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[[Image:3c7t.jpg|left|200px]]
 
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==Crystal structure of the ecdysone phosphate phosphatase, EPPase, from Bombix mori in complex with tungstate==
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The line below this paragraph, containing "STRUCTURE_3c7t", creates the "Structure Box" on the page.
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<StructureSection load='3c7t' size='340' side='right'caption='[[3c7t]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3c7t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C7T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C7T FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
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{{STRUCTURE_3c7t| PDB=3c7t | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c7t OCA], [https://pdbe.org/3c7t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c7t RCSB], [https://www.ebi.ac.uk/pdbsum/3c7t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c7t ProSAT]</span></td></tr>
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</table>
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===Crystal structure of the ecdysone phosphate phosphatase, EPPase, from Bombix mori in complex with tungstate===
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== Function ==
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[https://www.uniprot.org/uniprot/EPP_BOMMO EPP_BOMMO] Steroid phosphatase which catalyzes the conversion of inactive phosphorylated ecdysteroids into their active forms (PubMed:12721294, PubMed:15738639, PubMed:18937503). Shows high activity towards ecdysone 22-phosphate (E22P) (PubMed:12721294). Has lower activity towards other ecdysteriod phosphates including 20-hydroxyecdysone 22-phosphate (20E22P) and 2-deoxyecdysone 22-phosphate (2dE22P) (PubMed:12721294). Also has protein tyrosine phosphatase activity (PubMed:18937503).<ref>PMID:12721294</ref> <ref>PMID:15738639</ref> <ref>PMID:18937503</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_18937503}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18937503 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/3c7t_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18937503}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3C7T is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C7T OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c7t ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:18937503</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bombyx mori]]
[[Category: Bombyx mori]]
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[[Category: Carpino, N.]]
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[[Category: Large Structures]]
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[[Category: Chen, Y.]]
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[[Category: Carpino N]]
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[[Category: Nassar, N.]]
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[[Category: Chen Y]]
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[[Category: 2h-phosphatase]]
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[[Category: Nassar N]]
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[[Category: Ecdysone]]
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[[Category: Hydrolase]]
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[[Category: Pgm]]
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[[Category: Phosphatase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:22:46 2009''
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Current revision

Crystal structure of the ecdysone phosphate phosphatase, EPPase, from Bombix mori in complex with tungstate

PDB ID 3c7t

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