3fw6

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{{Seed}}
 
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[[Image:3fw6.png|left|200px]]
 
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==Crystal structure of CelM2, a bifunctional glucanase-xylanase protein from a metagenome library==
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The line below this paragraph, containing "STRUCTURE_3fw6", creates the "Structure Box" on the page.
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<StructureSection load='3fw6' size='340' side='right'caption='[[3fw6]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3fw6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Uncultured_bacterium Uncultured bacterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FW6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FW6 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3fw6| PDB=3fw6 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fw6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fw6 OCA], [https://pdbe.org/3fw6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fw6 RCSB], [https://www.ebi.ac.uk/pdbsum/3fw6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fw6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A1E9A6_9BACT A1E9A6_9BACT]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/3fw6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fw6 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Degradation of polysaccharides by cellulases and xylanases plays an important role in the carbon cycle, but only occurs in plant cell walls, a few bacteria and some animals. This process is also critical in processes such as biomass degradation and fuel production in the conversion cycles of cellulosic biomass. The enzyme CelM2 is bifunctional, because it is able to effectively hydrolyze barley glucan and xylan. Here, we show the crystal structure of the bifunctional enzyme CelM2, isolated from a metagenome library, and describe the sequence information and structure of its two domains. We believe that CelM2 is attractive as an industrial enzyme and that the structural results presented herein provide insights that are relevant to the genetic engineering of multifunctional enzymes.
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===Crystal structure of CelM2, a bifunctional glucanase-xylanase protein from a metagenome library===
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Crystal structure of CelM2, a bifunctional glucanase-xylanase protein from a metagenome library.,Nam KH, Kim SJ, Hwang KY Biochem Biophys Res Commun. 2009 May 29;383(2):183-6. Epub 2009 Apr 2. PMID:19345197<ref>PMID:19345197</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3fw6" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_19345197}}, adds the Publication Abstract to the page
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*[[Glucanase 3D structures|Glucanase 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 19345197 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_19345197}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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3FW6 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Uncultured_bacterium Uncultured bacterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FW6 OCA].
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==Reference==
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<ref group="xtra">PMID:19345197</ref><references group="xtra"/>
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[[Category: Cellulase]]
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[[Category: Uncultured bacterium]]
[[Category: Uncultured bacterium]]
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[[Category: Hwang, K Y.]]
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[[Category: Hwang KY]]
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[[Category: Nam, K H.]]
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[[Category: Nam KH]]
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[[Category: Bifunctional enzyme]]
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[[Category: Celm2]]
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[[Category: Glucanase]]
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[[Category: Glucanase-xyanase]]
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[[Category: Hydrolase]]
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[[Category: Xylanase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 09:49:19 2009''
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Current revision

Crystal structure of CelM2, a bifunctional glucanase-xylanase protein from a metagenome library

PDB ID 3fw6

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