3df6

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{{Seed}}
 
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[[Image:3df6.png|left|200px]]
 
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==The thermo- and acido-stable ORF-99 from the archaeal virus AFV1==
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The line below this paragraph, containing "STRUCTURE_3df6", creates the "Structure Box" on the page.
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<StructureSection load='3df6' size='340' side='right'caption='[[3df6]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3df6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Acidianus_filamentous_virus_1 Acidianus filamentous virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DF6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DF6 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_3df6| PDB=3df6 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3df6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3df6 OCA], [https://pdbe.org/3df6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3df6 RCSB], [https://www.ebi.ac.uk/pdbsum/3df6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3df6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Y099_AFV1Y Y099_AFV1Y]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Acidianus Filamentous Virus 1 (AFV1), isolated from acidic hot springs, is an enveloped lipid-containing archaeal filamentous virus with a linear double-stranded DNA genome. It infects Acidianus, which is a hyperthermostable archaea growing at 85 degrees C and acidic pHs, below pH 3. AFV1-99, a protein of 99 amino acids of unknown function, has homologues in the archaeal virus families Lipothrixviridae and Rudiviridae. We determined the crystal structure of AFV1-99 at 2.05 A resolution. AFV1-99 has a new fold, is hyperthermostable (up to 95 degrees C) and resists to extreme pH (between pH 0 and 11) and to the combination of high temperature (95 degrees C) and low pH (pH 0). It possesses characteristics of hyperthermostable proteins, such as a high content of charged residues.
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===ORF99 from the Archaeal Virus AFV1 is a Natural Mimic of the Ab-initio Designed Protein Top7===
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The thermo- and acido-stable ORF-99 from the archaeal virus AFV1.,Goulet A, Spinelli S, Blangy S, van Tilbeurgh H, Leulliot N, Basta T, Prangishvili D, Cambillau C, Campanacci V Protein Sci. 2009 Jun;18(6):1316-20. PMID:19472363<ref>PMID:19472363</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3df6" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 19472363 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_19472363}}
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__TOC__
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</StructureSection>
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==About this Structure==
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3DF6 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Acidianus_filamentous_virus_1 Acidianus filamentous virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DF6 OCA].
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==Reference==
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<ref group="xtra">PMID:19472363</ref><references group="xtra"/>
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[[Category: Acidianus filamentous virus 1]]
[[Category: Acidianus filamentous virus 1]]
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[[Category: Cambillau, C.]]
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[[Category: Large Structures]]
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[[Category: Campanacci, V.]]
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[[Category: Cambillau C]]
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[[Category: Goulet, A.]]
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[[Category: Campanacci V]]
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[[Category: Prangishvili, D.]]
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[[Category: Goulet A]]
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[[Category: Spinelli, S.]]
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[[Category: Prangishvili D]]
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[[Category: Tilbeurgh, H van.]]
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[[Category: Spinelli S]]
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[[Category: Archaeal virus]]
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[[Category: Van Tilbeurgh H]]
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[[Category: Extremophile]]
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[[Category: Lipothrixviridae]]
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[[Category: Protein fold]]
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[[Category: Unknown function]]
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[[Category: Viral protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 25 08:22:07 2009''
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Current revision

The thermo- and acido-stable ORF-99 from the archaeal virus AFV1

PDB ID 3df6

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