B-RAF with PLX4032
From Proteopedia
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<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br> | <scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br> | ||
<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/1'>Superposition</scene> | <scene name='B-RAF_with_PLX4032/Superposition3og71uwh/1'>Superposition</scene> | ||
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Revision as of 19:06, 5 October 2010
B-RAF with PLX4032
PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF.
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