B-RAF with PLX4032

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<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br>
<scene name='B-RAF_with_PLX4032/Phe_595_dfg_out/1'>DFG out</scene><br>
<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/1'>Superposition</scene>
<scene name='B-RAF_with_PLX4032/Superposition3og71uwh/1'>Superposition</scene>
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<applet load='3og7' size='600' color='white' frame='true' align='left' caption='testcaption' />
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<applet load='3og7' size='700' color='white' frame='true' align='center' caption='testcaption' />
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<applet load='1uwh' size='600' color='white' frame='true' align='right' caption='testcaption' />
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Revision as of 19:06, 5 October 2010

B-RAF with PLX4032

PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF.










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J.D. Woodruff, Jens Hemmingsen, Michal Harel

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