B-RAF with PLX4032

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<applet load='3og7' size='700' color='white' frame='true' align='right' caption='testcaption' />
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<applet load='3og7' size='800' color='white' frame='true' align='right' caption='testcaption' />
<scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br>
<scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br>
<scene name='B-RAF_with_PLX4032/Atp/1'>ATP</scene><br>
<scene name='B-RAF_with_PLX4032/Atp/1'>ATP</scene><br>

Revision as of 18:14, 7 October 2010

B-RAF with PLX4032

PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF.


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J.D. Woodruff, Jens Hemmingsen, Michal Harel

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