3mas
From Proteopedia
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{{STRUCTURE_3mas| PDB=3mas | SCENE= }} | {{STRUCTURE_3mas| PDB=3mas | SCENE= }} | ||
===Crystal structure of heterodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate=== | ===Crystal structure of heterodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate=== | ||
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{{ABSTRACT_PUBMED_20975740}} | {{ABSTRACT_PUBMED_20975740}} | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[3mas]] is a 2 chain structure of [[Isocitrate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MAS OCA]. | |
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+ | ==See Also== | ||
+ | *[[Isocitrate dehydrogenase|Isocitrate dehydrogenase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020975740</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Ding, J.]] | [[Category: Ding, J.]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Rossmann fold]] | [[Category: Rossmann fold]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 10 06:48:46 2010'' |
Revision as of 19:20, 26 July 2012
Contents |
Crystal structure of heterodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate
Template:ABSTRACT PUBMED 20975740
About this Structure
3mas is a 2 chain structure of Isocitrate dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yang B, Zhong C, Peng Y, Lai Z, Ding J. Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H. Cell Res. 2010 Nov;20(11):1188-200. Epub 2010 Oct 26. PMID:20975740 doi:10.1038/cr.2010.145