3mas

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[[Image:3mas.png|left|200px]]
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{{STRUCTURE_3mas| PDB=3mas | SCENE= }}
{{STRUCTURE_3mas| PDB=3mas | SCENE= }}
===Crystal structure of heterodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate===
===Crystal structure of heterodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate===
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{{ABSTRACT_PUBMED_20975740}}
{{ABSTRACT_PUBMED_20975740}}
==About this Structure==
==About this Structure==
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3MAS is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MAS OCA].
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[[3mas]] is a 2 chain structure of [[Isocitrate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MAS OCA].
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==See Also==
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*[[Isocitrate dehydrogenase|Isocitrate dehydrogenase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20975740</ref><references group="xtra"/>
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<ref group="xtra">PMID:020975740</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ding, J.]]
[[Category: Ding, J.]]
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[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Rossmann fold]]
[[Category: Rossmann fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 10 06:48:46 2010''
 

Revision as of 19:20, 26 July 2012

Template:STRUCTURE 3mas

Contents

Crystal structure of heterodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate

Template:ABSTRACT PUBMED 20975740

About this Structure

3mas is a 2 chain structure of Isocitrate dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Yang B, Zhong C, Peng Y, Lai Z, Ding J. Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H. Cell Res. 2010 Nov;20(11):1188-200. Epub 2010 Oct 26. PMID:20975740 doi:10.1038/cr.2010.145

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