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Zanamivir

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(New page: ===Pharmacokinetics=== {| class="wikitable" border="1" width="52%" style="text-align:center" |- ! colspan="12" align="center"| HIV Protease Inhibitor [[Pharmaceutical_Drugs#Pharmacokineti...)
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! colspan="12" align="center"| HIV Protease Inhibitor [[Pharmaceutical_Drugs#Pharmacokinetics_Translated|Pharmacokinetics]]<ref>PMID:20400409</ref><ref>Ferry et al, United States Patent US6147095, Pharmacia & Upjohn Company.</ref><ref>L. Veronese et al. Single-Dose Pharmacokinetics of Amprenavir, a Human Immunodeficiency Virus Type 1 Protease Inhibitor, in Subjects with Normal or Impaired Hepatic Function. Antimicrob Agents Chemother. 2000 April; 44(4): 821–826.</ref><ref>J. Ford, et al. Intracellular and Plasma Pharmacokinetics of Saquinavir-Ritonavir, Administered at 1,600/100 Milligrams Once Daily in Human Immunodeficiency Virus-Infected Patients. Antimicrob Agents Chemother. 2004 July; 48(7): 2388–2393.</ref><ref>PMID:10620574</ref><ref>PMID:16086644</ref><ref>PMID:19131522</ref><ref>PMID: 10952482</ref><ref>PMID:16338276</ref><ref>PMID:19729375</ref><ref>PMID:12668574</ref><ref>PMID:17255144</ref><ref>PMID:10858338</ref>
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! colspan="12" align="center"| Neuraminidase Inhibitor [[Pharmaceutical_Drugs#Pharmacokinetics_Translated|Pharmacokinetics]]
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Revision as of 14:55, 8 December 2010

Pharmacokinetics

Neuraminidase Inhibitor Pharmacokinetics
Parameter Ritonavir Oseltamivir
Tmax (hr) Ritonavir Oseltamivir
Cmax (ng/ml) Ritonavir Oseltamivir
Bioavailability (%) Ritonavir Oseltamivir
Protein Binding (%) Ritonavir Oseltamivir
T1/2 (hr) Ritonavir Oseltamivir
AUC (ng/ml/hr) Ritonavir Oseltamivir
Clearance (L/h) Ritonavir Oseltamivir
Dosage (mg) Ritonavir Oseltamivir
Metabolism Ritonavir Oseltamivir

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