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Zanamivir
From Proteopedia
(Difference between revisions)
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! [[Pharmaceutical_Drugs#Bioavailability_.28F.29|Bioavailability]] (%) | ! [[Pharmaceutical_Drugs#Bioavailability_.28F.29|Bioavailability]] (%) | ||
| - | ! | + | ! 2 |
! [[Oseltamivir]] | ! [[Oseltamivir]] | ||
|- | |- | ||
! [[Pharmaceutical_Drugs#Protein_Binding|Protein Binding]] (%) | ! [[Pharmaceutical_Drugs#Protein_Binding|Protein Binding]] (%) | ||
| - | ! | + | ! 10 |
! [[Oseltamivir]] | ! [[Oseltamivir]] | ||
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! Metabolism | ! Metabolism | ||
| - | ! | + | ! None |
! [[Oseltamivir]] | ! [[Oseltamivir]] | ||
|} | |} | ||
Revision as of 14:58, 8 December 2010
Pharmacokinetics
| Neuraminidase Inhibitor Pharmacokinetics[1] | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Parameter | Ritonavir | Oseltamivir | |||||||||
| Tmax (hr) | 1.25 | Oseltamivir | |||||||||
| Cmax (ng/ml) | 31.6 | Oseltamivir | |||||||||
| Bioavailability (%) | 2 | Oseltamivir | |||||||||
| Protein Binding (%) | 10 | Oseltamivir | |||||||||
| T1/2 (hr) | 3 | Oseltamivir | |||||||||
| AUC (ng/ml/hr) | 185 | Oseltamivir | |||||||||
| Clearance (L/h) | 54.1 | Oseltamivir | |||||||||
| Dosage (mg) | 10 | Oseltamivir | |||||||||
| Metabolism | None | Oseltamivir | |||||||||
