3gi2
From Proteopedia
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[[Image:3gi2.png|left|200px]] | [[Image:3gi2.png|left|200px]] | ||
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{{STRUCTURE_3gi2| PDB=3gi2 | SCENE= }} | {{STRUCTURE_3gi2| PDB=3gi2 | SCENE= }} | ||
===Human dihydrofolate reductase Q35K mutant inhibitor complex=== | ===Human dihydrofolate reductase Q35K mutant inhibitor complex=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Dihydrofolate reductase]] | + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019719239</ref><references group="xtra"/> |
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 10:03, 27 July 2012
Contents |
Human dihydrofolate reductase Q35K mutant inhibitor complex
Template:ABSTRACT PUBMED 19719239
About this Structure
3gi2 is a 1 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Gangjee A, Li W, Kisliuk RL, Cody V, Pace J, Piraino J, Makin J. Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents. J Med Chem. 2009 Aug 13;52(15):4892-902. PMID:19719239 doi:10.1021/jm900490a
