1j3j
From Proteopedia
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[[Image:1j3j.png|left|200px]] | [[Image:1j3j.png|left|200px]] | ||
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{{STRUCTURE_1j3j| PDB=1j3j | SCENE= }} | {{STRUCTURE_1j3j| PDB=1j3j | SCENE= }} | ||
===Double mutant (C59R+S108N) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with pyrimethamine, NADPH, and dUMP=== | ===Double mutant (C59R+S108N) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with pyrimethamine, NADPH, and dUMP=== | ||
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| - | The line below this paragraph, {{ABSTRACT_PUBMED_12704428}}, adds the Publication Abstract to the page | ||
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{{ABSTRACT_PUBMED_12704428}} | {{ABSTRACT_PUBMED_12704428}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1j3j]] is a 4 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3J OCA]. | + | [[1j3j]] is a 4 chain structure of [[Dihydrofolate reductase]] and [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3J OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Dihydrofolate reductase]] | + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] |
| + | *[[Thymidylate synthase|Thymidylate synthase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012704428</ref><references group="xtra"/> |
[[Category: Plasmodium falciparum]] | [[Category: Plasmodium falciparum]] | ||
[[Category: Chitnumsub, P.]] | [[Category: Chitnumsub, P.]] | ||
Revision as of 16:26, 25 July 2012
Contents |
Double mutant (C59R+S108N) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with pyrimethamine, NADPH, and dUMP
Template:ABSTRACT PUBMED 12704428
About this Structure
1j3j is a 4 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.
See Also
Reference
- Yuvaniyama J, Chitnumsub P, Kamchonwongpaisan S, Vanichtanankul J, Sirawaraporn W, Taylor P, Walkinshaw MD, Yuthavong Y. Insights into antifolate resistance from malarial DHFR-TS structures. Nat Struct Biol. 2003 May;10(5):357-65. PMID:12704428 doi:10.1038/nsb921
