3k47
From Proteopedia
(Difference between revisions)
m (Protected "3k47" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:3k47.png|left|200px]] | [[Image:3k47.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3k47", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3k47| PDB=3k47 | SCENE= }} | {{STRUCTURE_3k47| PDB=3k47 | SCENE= }} | ||
===Alternate Binding Modes Observed for the E- and Z-Isomers of 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase=== | ===Alternate Binding Modes Observed for the E- and Z-Isomers of 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_19748785}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 19748785 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_19748785}} | {{ABSTRACT_PUBMED_19748785}} | ||
| Line 22: | Line 11: | ||
==See Also== | ==See Also== | ||
| - | *[[Dihydrofolate reductase]] | + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019748785</ref><references group="xtra"/> |
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
Revision as of 22:22, 26 July 2012
Contents |
Alternate Binding Modes Observed for the E- and Z-Isomers of 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase
Template:ABSTRACT PUBMED 19748785
About this Structure
3k47 is a 1 chain structure of Dihydrofolate reductase with sequence from Mus musculus. Full crystallographic information is available from OCA.
See Also
Reference
- Gangjee A, Li W, Lin L, Zeng Y, Ihnat M, Warnke LA, Green DW, Cody V, Pace J, Queener SF. Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors. Bioorg Med Chem. 2009 Oct 15;17(20):7324-36. Epub 2009 Aug 22. PMID:19748785 doi:10.1016/j.bmc.2009.08.044
