2hhh
From Proteopedia
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[[Image:2hhh.png|left|200px]] | [[Image:2hhh.png|left|200px]] | ||
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{{STRUCTURE_2hhh| PDB=2hhh | SCENE= }} | {{STRUCTURE_2hhh| PDB=2hhh | SCENE= }} | ||
===Crystal structure of kasugamycin bound to the 30S ribosomal subunit=== | ===Crystal structure of kasugamycin bound to the 30S ribosomal subunit=== | ||
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{{ABSTRACT_PUBMED_16998488}} | {{ABSTRACT_PUBMED_16998488}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2hhh]] is a 21 chain structure of [[Ribosomal protein S10]], [[Ribosomal protein S11]], [[Ribosomal protein S12]], [[Ribosomal protein S13]], [[Ribosomal protein S15]], [[Ribosomal protein S17]], [[Ribosomal protein S2]], [[Ribosomal protein S20]], [[Ribosomal protein S3]], [[Ribosomal protein S4]] and [[Ribosomal protein THX]] with sequence from [http://en.wikipedia.org/wiki/ | + | [[2hhh]] is a 21 chain structure of [[Ribosomal protein S10]], [[Ribosomal protein S11]], [[Ribosomal protein S12]], [[Ribosomal protein S13]], [[Ribosomal protein S14]], [[Ribosomal protein S15]], [[Ribosomal protein S16]], [[Ribosomal protein S17]], [[Ribosomal protein S18]], [[Ribosomal protein S19]], [[Ribosomal protein S2]], [[Ribosomal protein S20]], [[Ribosomal protein S3]], [[Ribosomal protein S4]], [[Ribosomal protein S5]], [[Ribosomal protein S6]], [[Ribosomal protein S7]], [[Ribosomal protein S8]], [[Ribosomal protein S9]] and [[Ribosomal protein THX]] with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HHH OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Ribosomal protein S10]] | + | *[[Ribosomal protein S10|Ribosomal protein S10]] |
| - | *[[Ribosomal protein S11]] | + | *[[Ribosomal protein S11|Ribosomal protein S11]] |
| - | *[[Ribosomal protein S12]] | + | *[[Ribosomal protein S12|Ribosomal protein S12]] |
| - | *[[Ribosomal protein S13]] | + | *[[Ribosomal protein S13|Ribosomal protein S13]] |
| - | *[[Ribosomal protein S15]] | + | *[[Ribosomal protein S14|Ribosomal protein S14]] |
| - | *[[Ribosomal protein S17]] | + | *[[Ribosomal protein S15|Ribosomal protein S15]] |
| - | *[[Ribosomal protein S2]] | + | *[[Ribosomal protein S16|Ribosomal protein S16]] |
| - | *[[Ribosomal protein S20]] | + | *[[Ribosomal protein S17|Ribosomal protein S17]] |
| - | *[[Ribosomal protein S3]] | + | *[[Ribosomal protein S18|Ribosomal protein S18]] |
| - | *[[Ribosomal protein S4]] | + | *[[Ribosomal protein S19|Ribosomal protein S19]] |
| - | *[[Ribosomal protein THX]] | + | *[[Ribosomal protein S2|Ribosomal protein S2]] |
| + | *[[Ribosomal protein S20|Ribosomal protein S20]] | ||
| + | *[[Ribosomal protein S3|Ribosomal protein S3]] | ||
| + | *[[Ribosomal protein S4|Ribosomal protein S4]] | ||
| + | *[[Ribosomal protein S5|Ribosomal protein S5]] | ||
| + | *[[Ribosomal protein S6|Ribosomal protein S6]] | ||
| + | *[[Ribosomal protein S7|Ribosomal protein S7]] | ||
| + | *[[Ribosomal protein S8|Ribosomal protein S8]] | ||
| + | *[[Ribosomal protein S9|Ribosomal protein S9]] | ||
| + | *[[Ribosomal protein THX|Ribosomal protein THX]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016998488</ref><references group="xtra"/> |
| - | [[Category: Thermus thermophilus | + | [[Category: Thermus thermophilus]] |
[[Category: Schluenzen, F.]] | [[Category: Schluenzen, F.]] | ||
[[Category: 30]] | [[Category: 30]] | ||
Revision as of 18:53, 25 July 2012
Contents |
Crystal structure of kasugamycin bound to the 30S ribosomal subunit
Template:ABSTRACT PUBMED 16998488
About this Structure
2hhh is a 21 chain structure of Ribosomal protein S10, Ribosomal protein S11, Ribosomal protein S12, Ribosomal protein S13, Ribosomal protein S14, Ribosomal protein S15, Ribosomal protein S16, Ribosomal protein S17, Ribosomal protein S18, Ribosomal protein S19, Ribosomal protein S2, Ribosomal protein S20, Ribosomal protein S3, Ribosomal protein S4, Ribosomal protein S5, Ribosomal protein S6, Ribosomal protein S7, Ribosomal protein S8, Ribosomal protein S9 and Ribosomal protein THX with sequence from Thermus thermophilus. Full crystallographic information is available from OCA.
See Also
- Ribosomal protein S10
- Ribosomal protein S11
- Ribosomal protein S12
- Ribosomal protein S13
- Ribosomal protein S14
- Ribosomal protein S15
- Ribosomal protein S16
- Ribosomal protein S17
- Ribosomal protein S18
- Ribosomal protein S19
- Ribosomal protein S2
- Ribosomal protein S20
- Ribosomal protein S3
- Ribosomal protein S4
- Ribosomal protein S5
- Ribosomal protein S6
- Ribosomal protein S7
- Ribosomal protein S8
- Ribosomal protein S9
- Ribosomal protein THX
Reference
- Schluenzen F, Takemoto C, Wilson DN, Kaminishi T, Harms JM, Hanawa-Suetsugu K, Szaflarski W, Kawazoe M, Shirouzu M, Nierhaus KH, Yokoyama S, Fucini P. The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Nat Struct Mol Biol. 2006 Oct;13(10):871-8. Epub 2006 Sep 24. PMID:16998488 doi:10.1038/nsmb1145
