1dg8
From Proteopedia
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{{STRUCTURE_1dg8| PDB=1dg8 | SCENE= }} | {{STRUCTURE_1dg8| PDB=1dg8 | SCENE= }} | ||
===DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH=== | ===DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Dihydrofolate reductase]] | + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:010623528</ref><ref group="xtra">PMID:016648861</ref><references group="xtra"/> |
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
Revision as of 04:36, 26 July 2012
Contents |
DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH
Template:ABSTRACT PUBMED 10623528
About this Structure
1dg8 is a 1 chain structure of Dihydrofolate reductase with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
See Also
Reference
- Li R, Sirawaraporn R, Chitnumsub P, Sirawaraporn W, Wooden J, Athappilly F, Turley S, Hol WG. Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs. J Mol Biol. 2000 Jan 14;295(2):307-23. PMID:10623528 doi:http://dx.doi.org/10.1006/jmbi.1999.3328
- Argyrou A, Vetting MW, Aladegbami B, Blanchard JS. Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid. Nat Struct Mol Biol. 2006 May;13(5):408-13. Epub 2006 Apr 30. PMID:16648861 doi:10.1038/nsmb1089
Categories: Dihydrofolate reductase | Mycobacterium tuberculosis | Athappilly, F. | Chitnumsub, P. | Hol, W G. | Li, R. | Sirawaraporn, R. | Sirawaraporn, W. | Turley, S. | Wooden, J. | Folateanalog | Nicotinamide adenine dinucleotide | Oxidoreductase | Rossmann fold | Structure-based inhibitor design | Tuberculosis
