Sandbox Reserved 347

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=Introduction=
{{STRUCTURE_2iko | PDB=2iko | SCENE= }}
{{STRUCTURE_2iko | PDB=2iko | SCENE= }}
:Renin (pronounced /ˈriːnɨn/ REE-nin), also known as angiotensinogenase is an enzyme that participates in the body's renin-angiotensin system (RAS) that mediates extracellular volume (i.e., that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction.
:Renin (pronounced /ˈriːnɨn/ REE-nin), also known as angiotensinogenase is an enzyme that participates in the body's renin-angiotensin system (RAS) that mediates extracellular volume (i.e., that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction.
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::Thus, it regulates the body's mean arterial blood pressure.
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::Thus, it regulates the body's mean arterial blood pressure. <
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==Biochemistry==
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Renin is an aspartyl protease. <ref name= "Structure"> 2666611</ref>
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==Function==
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Renin plays a key role in the Renin-Angiotension sysmtem (RAS). This system is responsible for the control of blood pressure and salt balances in mammals.

Revision as of 23:02, 3 March 2011

This Sandbox is Reserved from January 10, 2010, through April 10, 2011 for use in BCMB 307-Proteins course taught by Andrea Gorrell at the University of Northern British Columbia, Prince George, BC, Canada.
To get started:
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  • Click the 3D button (when editing, above the wikitext box) to insert Jmol.
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More help: Help:Editing

Introduction

PDB ID 2iko

Drag the structure with the mouse to rotate
2iko, resolution 1.90Å ()
Ligands:
Gene: REN (Homo sapiens)
Activity: Renin, with EC number 3.4.23.15
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


Renin (pronounced /ˈriːnɨn/ REE-nin), also known as angiotensinogenase is an enzyme that participates in the body's renin-angiotensin system (RAS) that mediates extracellular volume (i.e., that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction.
Thus, it regulates the body's mean arterial blood pressure. <

Biochemistry

Renin is an aspartyl protease. [1]

Function

Renin plays a key role in the Renin-Angiotension sysmtem (RAS). This system is responsible for the control of blood pressure and salt balances in mammals.

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