Neuraminidase
From Proteopedia
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==3D structures of Neuraminidase== | ==3D structures of Neuraminidase== | ||
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===Neuraminidase=== | ===Neuraminidase=== | ||
| - | [[2ya4]], [[2w20]], [[2vvz]] – SpNANA catalytic domain – Streptococcus pneumoniae<br /> | + | [[2ya4]], [[2w20]], [[2vvz]] – SpNANA catalytic domain – ''Streptococcus pneumoniae''<br /> |
[[3h71]] - SpNANA catalytic domain precursor<br /> | [[3h71]] - SpNANA catalytic domain precursor<br /> | ||
[[2vw0]], [[2vw1]], [[2vw2]] - SpNANB<br /> | [[2vw0]], [[2vw1]], [[2vw2]] - SpNANB<br /> | ||
| - | [[2xzi]], [[2xzj]], [[2xzk]], [[2xcy]] – NANA – Aspergillus fumigatus<br /> | + | [[2xzi]], [[2xzj]], [[2xzk]], [[2xcy]] – NANA – ''Aspergillus fumigatus''<br /> |
| - | [[2w68]] – VcNANA sialic acid binding domain – Vibrio cholerae<br /> | + | [[2w68]] – VcNANA sialic acid binding domain – ''Vibrio cholerae''<br /> |
[[1w0o]], [[1kit]]– VcNANA<br /> | [[1w0o]], [[1kit]]– VcNANA<br /> | ||
[[1snt]], [[1so7]] – hNeu2 - human<br /> | [[1snt]], [[1so7]] – hNeu2 - human<br /> | ||
[[2f24]], [[2f26]], [[2f28]] – hNeu2 (mutant) <br /> | [[2f24]], [[2f26]], [[2f28]] – hNeu2 (mutant) <br /> | ||
| - | [[1eur]] - MvNANA residues 43-407 – Micromonospora viridifaciens<br /> | + | [[1eur]] - MvNANA residues 43-407 – ''Micromonospora viridifaciens''<br /> |
[[1euu]] - MvNANA residues 47-647<br /> | [[1euu]] - MvNANA residues 47-647<br /> | ||
[[1wcq]], [[1w8n]], [[1w8o]], [[2hu0]], [[2hu4]] – MvNANA residues 47-647 (mutant) <br /> | [[1wcq]], [[1w8n]], [[1w8o]], [[2hu0]], [[2hu4]] – MvNANA residues 47-647 (mutant) <br /> | ||
| - | [[3sil]] – StNANA (mutant) – Salmonella typhimurium | + | [[3sil]] – StNANA (mutant) – ''Salmonella typhimurium'' |
| - | Binary complexes | + | ''Binary complexes'' |
[[3h72]] - SpNANA catalytic domain precursor + sialic derivative<br /> | [[3h72]] - SpNANA catalytic domain precursor + sialic derivative<br /> | ||
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[[2qwa]] - IvNAN N9 Tern (mutant) | [[2qwa]] - IvNAN N9 Tern (mutant) | ||
| - | Binary | + | ''Binary complexe''s |
[[3o9j]], [[3o9k]], [[2c4a]], [[2c4l]], [[1w1x]], [[1w20]], [[1w21]], [[1nsb]], [[1nsc]], [[1nsd]] – IvNANA + sialic derivative<br /> | [[3o9j]], [[3o9k]], [[2c4a]], [[2c4l]], [[1w1x]], [[1w20]], [[1w21]], [[1nsb]], [[1nsc]], [[1nsd]] – IvNANA + sialic derivative<br /> | ||
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[[3gvl]] - ENANA<br /> | [[3gvl]] - ENANA<br /> | ||
| - | [[3gvf]], [[3gvk]] – ENANA (mutant) – Enterobacteria phage K1F | + | [[3gvf]], [[3gvk]] – ENANA (mutant) – ''Enterobacteria phage K1F'' |
===Pseudaminidase=== | ===Pseudaminidase=== | ||
| - | [[2w38]] – PNANA – Pseudomonas aeruginosa | + | [[2w38]] – PNANA – ''Pseudomonas aeruginosa'' |
===Trans-sialidase=== | ===Trans-sialidase=== | ||
[[2sli]], [[1sli]], [[3sli]] – lTS + inhibitor – leech | [[2sli]], [[1sli]], [[3sli]] – lTS + inhibitor – leech | ||
Revision as of 09:00, 11 May 2011
Avian Influenza Neuraminidase, Tamiflu and Relenza
Contents |
3D structures of Neuraminidase
Neuraminidase
2ya4, 2w20, 2vvz – SpNANA catalytic domain – Streptococcus pneumoniae
3h71 - SpNANA catalytic domain precursor
2vw0, 2vw1, 2vw2 - SpNANB
2xzi, 2xzj, 2xzk, 2xcy – NANA – Aspergillus fumigatus
2w68 – VcNANA sialic acid binding domain – Vibrio cholerae
1w0o, 1kit– VcNANA
1snt, 1so7 – hNeu2 - human
2f24, 2f26, 2f28 – hNeu2 (mutant)
1eur - MvNANA residues 43-407 – Micromonospora viridifaciens
1euu - MvNANA residues 47-647
1wcq, 1w8n, 1w8o, 2hu0, 2hu4 – MvNANA residues 47-647 (mutant)
3sil – StNANA (mutant) – Salmonella typhimurium
Binary complexes
3h72 - SpNANA catalytic domain precursor + sialic derivative
3h73 - SpNANA catalytic domain precursor + sialic acid analog
2ya5 - SpNANA catalytic domain + sialic acid
2ya7, 2ya8 - SpNANA catalytic domain + inhibitor
2ya6 - SpNANA catalytic domain + sialic acid analog
2jkb - SpNANB residues 30-697 + sialic acid analog
1w0p – VcNANA + sialic derivative
2f0z, 2f10, 2f11, 2f12, 2f13 – hNeu2 + inhibitor
2f25, 2f27, 2f29 - hNeu2 (mutant) + sialic acid analog
1vcu - hNeu2 + sialic acid analog
1eus - MvNANA residues 43-407 + neuraminic acid derivative
2bzd - MvNANA residues 47-647 (mutant) + galactose
1eut - MvNANA residues 47-647 + galactose
2ber - MvNANA residues 47-647 (mutant) + sialic derivative
1dil, 1dim – StNANA + inhibitor
2sim, 2sil - StNANA + neuraminic acid derivative
Influenza virus neuraminidase
3nss, 3k36, 3beq, 3cye, 2cml, 2b8h, 2ht5, 1v0z, 1nn2 – IvNANA residues 82-469 – Influenza virus
3k38 – IvNANA (mutant)
2ht5 – IvNAN N8 residues 82-469
2htv - IvNAN N4 residues 82-469
2hty - IvNAN N1 residues 82-469
3nn9, 4nn9, 5nn9, 6nn9 - IvNAN N9 residues 82-469
7nn9 - IvNAN N9 Tern
2qwa - IvNAN N9 Tern (mutant)
Binary complexes
3o9j, 3o9k, 2c4a, 2c4l, 1w1x, 1w20, 1w21, 1nsb, 1nsc, 1nsd – IvNANA + sialic derivative
3k37, 3b7e, 1vcj, 1l7f, 1f8c, 1f8d, 1f8e, 1a4g, 1a4q, 1b9t, 1b9v, 1b9s, 1inf, 1ing, 1inh, 1ivb, 1ivc, 1ivd, 1ive, 1ivf, 1ivg – IvNANA + inhibitor
1f8b, 1inv, 1inw, 1inx, 1iny – IvNANA + sialic acid analog
2ht7, 2ht8, 2htq, 2htu – IvNAN N8 + inhibitor
2htr – IvNAN N8 + sialic acid analog
2htw - IvNAN N4 + sialic acid analog
2bat – IvNAN N2 + sialic acid
1nna, 1nnb - IvNAN N9 + neuraminic acid derivative
1xoe, 1xog - IvNAN N9 Tern + inhibitor
2qwb - IvNAN N9 Tern (mutant) + sialic derivative
2qwc, 2qwd, 2qwe - IvNAN N9 Tern (mutant) + sialic acid analog
1mwe - IvNAN N9 Tern + sialic acid
1bji, 1nnc - IvNAN N9 Tern + sialic acid analog
2qwf, 2qwg, 2qwh, 2qwi, 2qwj, 2qwk - IvNAN N9 Tern (mutant) + inhibitor
1nma, 1nmb - IvNAN N9 Tern + mFAB heavy+light chain – mouse
1nca, 1ncb, 1ncc, 1ncd - IvNAN N9 + mFAB heavy+light chain
3k39, 3k3a, 3ckz, 3cl0, 3cl2, 1l7g, 1l7h - IvNANA (mutant) + inhibitor
2aep, 2aeq – IvNANA + mFAB heavy+light chain
Endo-neuraminidase
3gvl - ENANA
3gvf, 3gvk – ENANA (mutant) – Enterobacteria phage K1F
Pseudaminidase
2w38 – PNANA – Pseudomonas aeruginosa
Trans-sialidase
2sli, 1sli, 3sli – lTS + inhibitor – leech
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Eran Hodis
