This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2l28
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
[[Image:2l28.png|left|200px]] | [[Image:2l28.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2l28", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2l28| PDB=2l28 | SCENE= }} | {{STRUCTURE_2l28| PDB=2l28 | SCENE= }} | ||
===Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers=== | ===Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_21410224}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 21410224 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_21410224}} | {{ABSTRACT_PUBMED_21410224}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2l28]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_casei Lactobacillus casei]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L28 OCA]. | + | [[2l28]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_casei Lactobacillus casei]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L28 OCA]. |
| + | |||
| + | ==See Also== | ||
| + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
==Reference== | ==Reference== | ||
| Line 28: | Line 20: | ||
[[Category: Feeney, J.]] | [[Category: Feeney, J.]] | ||
[[Category: Polshakov, V I.]] | [[Category: Polshakov, V I.]] | ||
| + | [[Category: Antifolate]] | ||
| + | [[Category: Co-operative binding]] | ||
| + | [[Category: Dhfr]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 10:57, 25 July 2012
Contents |
Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers
Template:ABSTRACT PUBMED 21410224
About this Structure
2l28 is a 1 chain structure of Dihydrofolate reductase with sequence from Lactobacillus casei. Full experimental information is available from OCA.
See Also
Reference
- Feeney J, Birdsall B, Kovalevskaya NV, Smurnyy YD, Navarro-Peran EM, Polshakov VI. NMR structures of apo L.casei dihydrofolate reductase and its complexes with trimethoprim and NADPH. Contributions to positive cooperative binding from ligand-induced refolding, conformational changes and interligand hydrophobic interactionsdagger. Biochemistry. 2011 Mar 16. PMID:21410224 doi:10.1021/bi200067t
