Multiple sclerosis

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'''Please have patience as I edit this page over the next few weeks! Thank you!'''--[[User:Kirsten Eldredge|Kirsten Eldredge]] 04:22, 9 April 2012 (IDT)
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'''Please have patience as I edit this page over the next week! Thank you!'''--[[User:Kirsten Eldredge|Kirsten Eldredge]] 04:06, 21 April 2012 (IDT)
<StructureSection load='1ifa' size='500' side='right' caption='Click on the green links to the left to see key structural features of Interferon Beta (PDB entry [[1ifa]])' scene='Multiple_sclerosis/Interferon_beta/1'>
<StructureSection load='1ifa' size='500' side='right' caption='Click on the green links to the left to see key structural features of Interferon Beta (PDB entry [[1ifa]])' scene='Multiple_sclerosis/Interferon_beta/1'>
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=== A comparison of Interferon Alpha to Interferon Beta ===
=== A comparison of Interferon Alpha to Interferon Beta ===
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<center>
{|
{|
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|<applet load='1itf.pdb' name='A' size='250' frame='true' align='right' caption='Interferon Alpha' align='left' scene='Multiple_sclerosis/Ifna_take_3/4'/>
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|<applet load='1itf.pdb' name='A' size='250' frame='true' align='right' caption='Interferon Alpha' align='left' scene='Multiple_sclerosis/Ifna_take_2/1'/>
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|<applet load='1ifa.pdb' name='B' size='250' frame='true' align='right' caption='Interferon Beta' align='left' scene='Multiple_sclerosis/Ifnb_take_2/2'/>
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|<applet load='1ifa.pdb' name='B' size='250' frame='true' align='right' caption='Interferon Beta' align='left' scene='Multiple_sclerosis/Ifnb_take_2/1'/>
|}
|}
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{{Clear}}
 
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<center>
 
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'''Synchronize the applets showing Interferons Alpha and Beta by clicking the checkbox'''
 
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<jmol>
 
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<jmolCheckbox>
 
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<target>A</target>
 
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<!--<scriptWhenChecked>set syncMouse ON;set syncScript OFF;sync jmolAppletB; sync > "set syncMouse
 
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ON;set syncScript OFF"</scriptWhenChecked>-->
 
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<scriptWhenChecked> sync jmolAppletB </scriptWhenChecked>
 
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<scriptWhenUnchecked> sync OFF</scriptWhenUnchecked>
 
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<text> Synchronize</text>
 
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</jmolCheckbox>
 
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</jmol>
 
</center>
</center>
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{{Clear}}
{{Clear}}

Revision as of 01:06, 21 April 2012

Please have patience as I edit this page over the next week! Thank you!--Kirsten Eldredge 04:06, 21 April 2012 (IDT)

Click on the green links to the left to see key structural features of Interferon Beta (PDB entry 1ifa)

Drag the structure with the mouse to rotate

Other Treatments

Copaxone

References

  1. ↑ Voet, D., Voet, J.G., and C. Pratt. Fundamentals of Biochemistry 3rd Edition. Hoboken, NJ: John Wiley and Sons, 2008. Print.
  2. ↑ Kudo M. Management of hepatocellular carcinoma: from prevention to molecular targeted therapy. Oncology. 2010 Jul;78 Suppl 1:1-6. Epub 2010 Jul 8. PMID:20616576 doi:10.1159/000315222
  3. ↑ http://www.uniprot.org/uniprot/P00784
  4. ↑ [1] Samuel, C.E. "Interferons, Interferon Receptors, Signal Transducer and Transcriptional Activators, and Inteferon Regulatory Factors." J Biol Chem 2007 282: 20045-20046. First Published on May 14, 2007, doi:10.1074/jbc.R700025200
  5. ↑ Chill JH, Quadt SR, Levy R, Schreiber G, Anglister J. The human type I interferon receptor: NMR structure reveals the molecular basis of ligand binding. Structure. 2003 Jul;11(7):791-802. PMID:12842042

Relevant 3D Structures

Interferon Beta

1au1 - Homo sapiens

1ifa, 1wu3 - Mus musculus

Interferon Receptors

3s98, 3se3, 3se4, 1n6u, 1n6v, 2hym, 2kz1, 2lag, 3s8w, 3s9d - Homo sapiens

Proteopedia Page Contributors and Editors (what is this?)

Kirsten Eldredge

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