User:Gisselle Medina/Sandbox7 Leader
From Proteopedia
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==Structure== | ==Structure== | ||
<Structure load='2JQG' size='400' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | <Structure load='2JQG' size='400' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
| - | Lpro upon translation frees itself from the growing polypeptide. This self-processing event is believed to occurred intramolecularly due to the presence of a flexible <scene name='User:Gisselle_Medina/Sandbox7_Leader/C_terminal_extension/2'>C-terminal extension</scene> which contributes to self-processing. | + | The leader protein from FMDV is a cysteine protease and constitutes a virulent factor during FMDV infection. It is the first protein that is translated from the growing polyprotein and Lpro upon translation frees itself from the growing polypeptide. This self-processing event is believed to occurred intramolecularly due to the presence of a flexible <scene name='User:Gisselle_Medina/Sandbox7_Leader/C_terminal_extension/2'>C-terminal extension</scene> which contributes to self-processing. |
CTE is composed of 18 amino acid residues and presumably can fold back into its own active site. <scene name='User:Gisselle_Medina/Sandbox7_Leader/Active_site_mutated/1'>active site</scene> | CTE is composed of 18 amino acid residues and presumably can fold back into its own active site. <scene name='User:Gisselle_Medina/Sandbox7_Leader/Active_site_mutated/1'>active site</scene> | ||
Revision as of 14:52, 16 May 2014
Introduction
Structure
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The leader protein from FMDV is a cysteine protease and constitutes a virulent factor during FMDV infection. It is the first protein that is translated from the growing polyprotein and Lpro upon translation frees itself from the growing polypeptide. This self-processing event is believed to occurred intramolecularly due to the presence of a flexible which contributes to self-processing. CTE is composed of 18 amino acid residues and presumably can fold back into its own active site.
