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2lrf

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'''Unreleased structure'''
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{{STRUCTURE_2lrf| PDB=2lrf | SCENE= }}
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===NMR structure of the Scylla Serrata anti lipopolysaccharide Factor-24 (SsALF-24) peptide===
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The entry 2lrf is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/ALPS_SCYSE ALPS_SCYSE]] Binds to bacterial LPS and may specifically inhibit the LPS-mediated activation of the hemolymph coagulation. It has a strong antibacterial effect especially on the growth of Gram-negative bacteria.<ref>PMID:19490944</ref> <ref>PMID:21195157</ref>
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Authors: Reddy, K.V.R., Sharma, S., Yedery, R., Barnwal, R.P.
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==About this Structure==
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[[2lrf]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LRF OCA].
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Description: NMR structure of the Scylla Serrata anti lipopolysaccharide Factor-24 (SsALF-24) peptide
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Barnwal, R P.]]
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[[Category: Reddy, K V.R.]]
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[[Category: Sharma, S.]]
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[[Category: Yedery, R.]]
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[[Category: Antimicrobial]]
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[[Category: Antimicrobial protein]]

Revision as of 01:37, 4 April 2013

Template:STRUCTURE 2lrf

Contents

NMR structure of the Scylla Serrata anti lipopolysaccharide Factor-24 (SsALF-24) peptide

Function

[ALPS_SCYSE] Binds to bacterial LPS and may specifically inhibit the LPS-mediated activation of the hemolymph coagulation. It has a strong antibacterial effect especially on the growth of Gram-negative bacteria.[1] [2]

About this Structure

2lrf is a 1 chain structure. Full experimental information is available from OCA.

Reference

  1. ↑ Yedery RD, Reddy KV. Identification, cloning, characterization and recombinant expression of an anti-lipopolysaccharide factor from the hemocytes of Indian mud crab, Scylla serrata. Fish Shellfish Immunol. 2009 Aug;27(2):275-84. doi: 10.1016/j.fsi.2009.05.009., Epub 2009 May 31. PMID:19490944 doi:10.1016/j.fsi.2009.05.009
  2. ↑ Sharma S, Yedery RD, Patgaonkar MS, Selvaakumar C, Reddy KV. Antibacterial activity of a synthetic peptide that mimics the LPS binding domain of Indian mud crab, Scylla serrata anti-lipopolysaccharide factor (SsALF) also involved in the modulation of vaginal immune functions through NF-kB signaling. Microb Pathog. 2011 Mar-Apr;50(3-4):179-91. doi: 10.1016/j.micpath.2010.12.007., Epub 2010 Dec 30. PMID:21195157 doi:10.1016/j.micpath.2010.12.007

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