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3cl9
From Proteopedia
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[[Image:3cl9.png|left|200px]] | [[Image:3cl9.png|left|200px]] | ||
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{{STRUCTURE_3cl9| PDB=3cl9 | SCENE= }} | {{STRUCTURE_3cl9| PDB=3cl9 | SCENE= }} | ||
===Structure of bifunctional TcDHFR-TS in complex with MTX=== | ===Structure of bifunctional TcDHFR-TS in complex with MTX=== | ||
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Revision as of 00:32, 26 July 2012
Contents |
Structure of bifunctional TcDHFR-TS in complex with MTX
Template:ABSTRACT PUBMED 18536013
About this Structure
3cl9 is a 1 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.
See Also
Reference
- Schormann N, Senkovich O, Walker K, Wright DL, Anderson AC, Rosowsky A, Ananthan S, Shinkre B, Velu S, Chattopadhyay D. Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins. 2008 Dec;73(4):889-901. PMID:18536013 doi:10.1002/prot.22115
Categories: Trypanosoma cruzi | Chattopadhyay, D. | Schormann, N. | Senkovich, O. | Bifunctional enzyme in complex with nadp | Methyltransferase | Mtx and dump | Multifunctional enzyme | Nucleotide biosynthesis | One-carbon metabolism | Oxidoreductase | Oxidoreductase-transferase complex | Transferase
