3frd

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==About this Structure==
==About this Structure==
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[[3frd]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRD OCA].
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[[3frd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRD OCA].
==See Also==
==See Also==

Revision as of 09:39, 20 October 2012

Template:STRUCTURE 3frd

Contents

S. aureus DHFR complexed with NADPH and folate

Template:ABSTRACT PUBMED 19211577

About this Structure

3frd is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

See Also

Reference

  • Oefner C, Bandera M, Haldimann A, Laue H, Schulz H, Mukhija S, Parisi S, Weiss L, Lociuro S, Dale GE. Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity. J Antimicrob Chemother. 2009 Apr;63(4):687-98. Epub 2009 Feb 11. PMID:19211577 doi:10.1093/jac/dkp024

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