1hfr
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[1hfr]] is a 1 chain structure | + | [[1hfr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HFR OCA]. |
==See Also== | ==See Also== | ||
Revision as of 14:34, 20 October 2012
Contents |
COMPARISON OF TERNARY CRYSTAL COMPLEXES OF HUMAN DIHYDROFOLATE REDUCTASE WITH NADPH AND A CLASSICAL ANTITUMOR FUROPYRIMDINE
Template:ABSTRACT PUBMED 9627670
About this Structure
1hfr is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Cody V, Galitsky N, Luft JR, Pangborn W, Blakley RL, Gangjee A. Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine. Anticancer Drug Des. 1998 Jun;13(4):307-15. PMID:9627670
- Yuvaniyama J, Chitnumsub P, Kamchonwongpaisan S, Vanichtanankul J, Sirawaraporn W, Taylor P, Walkinshaw MD, Yuthavong Y. Insights into antifolate resistance from malarial DHFR-TS structures. Nat Struct Biol. 2003 May;10(5):357-65. PMID:12704428 doi:10.1038/nsb921
