3dat

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:3dat.png|left|200px]]
 
- 
{{STRUCTURE_3dat| PDB=3dat | SCENE= }}
{{STRUCTURE_3dat| PDB=3dat | SCENE= }}
- 
===Crystal structure of the ternary MTX NADPH complex of Bacillus anthracis dihydrofolate reductase===
===Crystal structure of the ternary MTX NADPH complex of Bacillus anthracis dihydrofolate reductase===
 +
{{ABSTRACT_PUBMED_19374017}}
-
{{ABSTRACT_PUBMED_19374017}}
+
==Function==
 +
[[http://www.uniprot.org/uniprot/Q81R22_BACAN Q81R22_BACAN]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]
==About this Structure==
==About this Structure==
-
[[3dat]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_str._sterne Bacillus anthracis str. sterne]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DAT OCA].
+
[[3dat]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_(strain_sterne) Bacillus anthracis (strain sterne)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DAT OCA].
==See Also==
==See Also==
Line 14: Line 13:
==Reference==
==Reference==
-
<ref group="xtra">PMID:019374017</ref><references group="xtra"/>
+
<ref group="xtra">PMID:019374017</ref><references group="xtra"/><references/>
-
[[Category: Bacillus anthracis str. sterne]]
+
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Bennett, B C.]]
[[Category: Bennett, B C.]]

Revision as of 12:21, 20 November 2013

Template:STRUCTURE 3dat

Contents

Crystal structure of the ternary MTX NADPH complex of Bacillus anthracis dihydrofolate reductase

Template:ABSTRACT PUBMED 19374017

Function

[Q81R22_BACAN] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]

About this Structure

3dat is a 1 chain structure with sequence from Bacillus anthracis (strain sterne). Full crystallographic information is available from OCA.

See Also

Reference

  • Bennett BC, Wan Q, Ahmad MF, Langan P, Dealwis CG. X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design. J Struct Biol. 2009 May;166(2):162-71. PMID:19374017

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3dat"
Personal tools