3kfy
From Proteopedia
(Difference between revisions)
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- | + | ==Dynamic switching and partial occupancies of a small molecule inhibitor complex of DHFR== | |
- | + | <StructureSection load='3kfy' size='340' side='right' caption='[[3kfy]], [[Resolution|resolution]] 2.08Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[3kfy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KFY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KFY FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=JZM:5-[(4-CHLOROPHENYL)SULFANYL]QUINAZOLINE-2,4-DIAMINE'>JZM</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr> | |
- | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dhf|1dhf]], [[3k45|3k45]]</td></tr> | |
- | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | |
- | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kfy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kfy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kfy RCSB], [http://www.ebi.ac.uk/pdbsum/3kfy PDBsum]</span></td></tr> |
- | [[3kfy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KFY OCA]. | + | </table> |
==See Also== | ==See Also== | ||
*[[Dihydrofolate reductase|Dihydrofolate reductase]] | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
- | [[Category: Carroll, M J | + | [[Category: Carroll, M J]] |
- | [[Category: Collins, E J | + | [[Category: Collins, E J]] |
- | [[Category: Gromova, A V | + | [[Category: Gromova, A V]] |
- | [[Category: Lee, A L | + | [[Category: Lee, A L]] |
- | [[Category: Miller, K R | + | [[Category: Miller, K R]] |
- | [[Category: Singleton, S F | + | [[Category: Singleton, S F]] |
[[Category: Antibiotic resistance]] | [[Category: Antibiotic resistance]] | ||
[[Category: Dynamic]] | [[Category: Dynamic]] |
Revision as of 09:21, 9 December 2014
Dynamic switching and partial occupancies of a small molecule inhibitor complex of DHFR
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Categories: Dihydrofolate reductase | Escherichia coli | Carroll, M J | Collins, E J | Gromova, A V | Lee, A L | Miller, K R | Singleton, S F | Antibiotic resistance | Dynamic | Methotrexate resistance | Nadp | One-carbon metabolism | Oxidoreductase | Small molecule inhibitor | Trimethoprim resistance