3kfy

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[[Image:3kfy.png|left|200px]]
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==Dynamic switching and partial occupancies of a small molecule inhibitor complex of DHFR==
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<StructureSection load='3kfy' size='340' side='right' caption='[[3kfy]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
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{{STRUCTURE_3kfy| PDB=3kfy | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3kfy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KFY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KFY FirstGlance]. <br>
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===Dynamic switching and partial occupancies of a small molecule inhibitor complex of DHFR===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=JZM:5-[(4-CHLOROPHENYL)SULFANYL]QUINAZOLINE-2,4-DIAMINE'>JZM</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dhf|1dhf]], [[3k45|3k45]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kfy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kfy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kfy RCSB], [http://www.ebi.ac.uk/pdbsum/3kfy PDBsum]</span></td></tr>
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[[3kfy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KFY OCA].
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</table>
==See Also==
==See Also==
*[[Dihydrofolate reductase|Dihydrofolate reductase]]
*[[Dihydrofolate reductase|Dihydrofolate reductase]]
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__TOC__
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</StructureSection>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Carroll, M J.]]
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[[Category: Carroll, M J]]
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[[Category: Collins, E J.]]
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[[Category: Collins, E J]]
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[[Category: Gromova, A V.]]
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[[Category: Gromova, A V]]
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[[Category: Lee, A L.]]
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[[Category: Lee, A L]]
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[[Category: Miller, K R.]]
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[[Category: Miller, K R]]
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[[Category: Singleton, S F.]]
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[[Category: Singleton, S F]]
[[Category: Antibiotic resistance]]
[[Category: Antibiotic resistance]]
[[Category: Dynamic]]
[[Category: Dynamic]]

Revision as of 09:21, 9 December 2014

Dynamic switching and partial occupancies of a small molecule inhibitor complex of DHFR

3kfy, resolution 2.08Å

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