3tq9

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[[Image:3tq9.png|left|200px]]
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==Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexate==
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<StructureSection load='3tq9' size='340' side='right' caption='[[3tq9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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{{STRUCTURE_3tq9| PDB=3tq9 | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3tq9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Coxiella_burnetii Coxiella burnetii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TQ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TQ9 FirstGlance]. <br>
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===Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexate===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tq8|3tq8]], [[3tqa|3tqa]], [[3tqb|3tqb]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CBU_1993, folA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=777 Coxiella burnetii])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr>
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[[3tq9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Coxiella_burnetii Coxiella burnetii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TQ9 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tq9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tq9 RCSB], [http://www.ebi.ac.uk/pdbsum/3tq9 PDBsum]</span></td></tr>
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</table>
==See Also==
==See Also==
*[[Dihydrofolate reductase|Dihydrofolate reductase]]
*[[Dihydrofolate reductase|Dihydrofolate reductase]]
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__TOC__
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</StructureSection>
[[Category: Coxiella burnetii]]
[[Category: Coxiella burnetii]]
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
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[[Category: Cassidy, M.]]
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[[Category: Cassidy, M]]
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[[Category: Franklin, M C.]]
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[[Category: Franklin, M C]]
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[[Category: Hillerich, B.]]
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[[Category: Hillerich, B]]
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[[Category: Love, J.]]
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[[Category: Love, J]]
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[[Category: Dihydrofolate reductase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 16:29, 9 December 2014

Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexate

3tq9, resolution 2.30Å

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