2cgt
From Proteopedia
(Difference between revisions)
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| - | [[Image:2cgt.png|left|200px]] | ||
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{{STRUCTURE_2cgt| PDB=2cgt | SCENE= }} | {{STRUCTURE_2cgt| PDB=2cgt | SCENE= }} | ||
| + | ===GROEL-ADP-gp31 COMPLEX=== | ||
| + | {{ABSTRACT_PUBMED_16549073}} | ||
| - | === | + | ==Function== |
| - | + | [[http://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600] [[http://www.uniprot.org/uniprot/VG31_BPT4 VG31_BPT4]] Essential for proper capsid assembly. In absence of Gp31 the major capsid protein (Gp23) assembles into 'lumps'. Acts as a co-chaperonin with the host groEL protein. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:016549073</ref><references group="xtra"/> | + | <ref group="xtra">PMID:016549073</ref><references group="xtra"/><references/> |
[[Category: Enterobacteria phage t4]] | [[Category: Enterobacteria phage t4]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Bakkes, P J.]] | [[Category: Bakkes, P J.]] | ||
[[Category: Clare, D K.]] | [[Category: Clare, D K.]] | ||
| - | [[Category: Heerikhuizen, H | + | [[Category: Heerikhuizen, H van.]] |
[[Category: Saibil, H R.]] | [[Category: Saibil, H R.]] | ||
| - | [[Category: Vies, S M. | + | [[Category: Vies, S M.van der.]] |
[[Category: Capsid assembly]] | [[Category: Capsid assembly]] | ||
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
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[[Category: Chaperonin]] | [[Category: Chaperonin]] | ||
[[Category: Early protein]] | [[Category: Early protein]] | ||
| - | [[Category: Gp31]] | ||
| - | [[Category: Groel]] | ||
Revision as of 19:15, 7 August 2013
Contents |
GROEL-ADP-gp31 COMPLEX
Template:ABSTRACT PUBMED 16549073
Function
[CH60_ECOLI] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600] [VG31_BPT4] Essential for proper capsid assembly. In absence of Gp31 the major capsid protein (Gp23) assembles into 'lumps'. Acts as a co-chaperonin with the host groEL protein.
About this Structure
2cgt is a 21 chain structure with sequence from Enterobacteria phage t4 and Escherichia coli. Full crystallographic information is available from OCA.
See Also
Reference
- Clare DK, Bakkes PJ, van Heerikhuizen H, van der Vies SM, Saibil HR. An expanded protein folding cage in the GroEL-gp31 complex. J Mol Biol. 2006 May 5;358(3):905-11. Epub 2006 Mar 6. PMID:16549073 doi:10.1016/j.jmb.2006.02.033
