This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1w21
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | ==STRUCTURE OF NEURAMINIDASE FROM ENGLISH DUCK SUBTYPE N6 COMPLEXED WITH 30 MM SIALIC ACID (NANA, NEU5AC), CRYSTAL SOAKED FOR 43 HOURS AT 291 K.== | |
| - | + | <StructureSection load='1w21' size='340' side='right' caption='[[1w21]], [[Resolution|resolution]] 2.08Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1w21]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W21 FirstGlance]. <br> | |
| - | + | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene><br> | |
| - | + | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a14|1a14]], [[1a4g|1a4g]], [[1a4q|1a4q]], [[1b9s|1b9s]], [[1b9t|1b9t]], [[1b9v|1b9v]], [[1bji|1bji]], [[1e8t|1e8t]], [[1e8u|1e8u]], [[1e8v|1e8v]], [[1euu|1euu]], [[1f8b|1f8b]], [[1f8c|1f8c]], [[1f8d|1f8d]], [[1f8e|1f8e]], [[1inf|1inf]], [[1ing|1ing]], [[1inh|1inh]], [[1inv|1inv]], [[1inw|1inw]], [[1inx|1inx]], [[1iny|1iny]], [[1ivb|1ivb]], [[1ivc|1ivc]], [[1ivd|1ivd]], [[1ive|1ive]], [[1ivf|1ivf]], [[1ivg|1ivg]], [[1kit|1kit]], [[1l7f|1l7f]], [[1l7g|1l7g]], [[1l7h|1l7h]], [[1mwe|1mwe]], [[1nca|1nca]], [[1ncb|1ncb]], [[1ncc|1ncc]], [[1ncd|1ncd]], [[1nma|1nma]], [[1nmb|1nmb]], [[1nmc|1nmc]], [[1nn2|1nn2]], [[1nna|1nna]], [[1nnb|1nnb]], [[1nnc|1nnc]], [[1nsb|1nsb]], [[1nsc|1nsc]], [[1nsd|1nsd]], [[1usr|1usr]], [[1usx|1usx]], [[1v2i|1v2i]], [[1v3b|1v3b]], [[1v3c|1v3c]], [[1v3d|1v3d]], [[1v3e|1v3e]], [[1vcj|1vcj]], [[1w1x|1w1x]], [[1w20|1w20]], [[1v0z|1v0z]], [[1w8n|1w8n]], [[1w8o|1w8o]], [[1xoe|1xoe]], [[1xog|1xog]], [[1z4v|1z4v]], [[1z4w|1z4w]], [[1z4x|1z4x]], [[1z4y|1z4y]], [[1z4z|1z4z]], [[1z50|1z50]], [[2bat|2bat]], [[2qwa|2qwa]], [[2qwb|2qwb]], [[2qwc|2qwc]], [[2qwd|2qwd]], [[2qwe|2qwe]], [[2qwf|2qwf]], [[2qwg|2qwg]], [[2qwh|2qwh]], [[2qwi|2qwi]], [[2qwj|2qwj]], [[2qwk|2qwk]], [[2sil|2sil]], [[2sim|2sim]], [[3nn9|3nn9]], [[4nn9|4nn9]], [[5nn9|5nn9]], [[6nn9|6nn9]], [[7nn9|7nn9]]</td></tr> | |
| - | + | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr> | |
| - | == | + | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w21 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w21 RCSB], [http://www.ebi.ac.uk/pdbsum/1w21 PDBsum]</span></td></tr> |
| - | [[1w21]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W21 OCA]. | + | <table> |
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w2/1w21_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Neuraminidase|Neuraminidase]] | *[[Neuraminidase|Neuraminidase]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Exo-alpha-sialidase]] | [[Category: Exo-alpha-sialidase]] | ||
[[Category: Influenza a virus]] | [[Category: Influenza a virus]] | ||
Revision as of 22:15, 28 September 2014
STRUCTURE OF NEURAMINIDASE FROM ENGLISH DUCK SUBTYPE N6 COMPLEXED WITH 30 MM SIALIC ACID (NANA, NEU5AC), CRYSTAL SOAKED FOR 43 HOURS AT 291 K.
| |||||||||||
