Nonstructural protein

From Proteopedia

Revision as of 12:49, 7 February 2013

Template:STRUCTURE 3o9s

Nonstructural protein (NS) is a protein encoded by a virus which is not part of the viral particle. The images at the left and at the right correspond to one representative NS, i.e. the crystal structure of Nonstructural protein from Influenza virus (3o9s). For homology model and multiple sequence alignment see User:Michael Strong/H1N1/NS, User:Michael Strong/H1N1/NS1/MSA and User:Michael Strong/H1N1/NS2/MSA.

3D Structures of Nonstructural protein

Updated June 2012

3o9q – IvNS1 (mutant) – Influenza virus
3o9r, 3o9s, 3o9t, 3o9u, 3f5t – IvNS1
3m8a, 2z0a, 1xeq, 1ail – IvNS1 RNA-binding domain
3p31 – IvNS1 C terminal effector domain
3p38, 3p39 – IvNS1 C terminal effector domain (mutant)
1ns1 - IvNS1 RNA-binding domain - NMR
3m5r, 2gx9 - IvNS1 effector domain
1pd3 – IvNS2 M1-binding domain
3l6p, 3lkw – DvNS2B/3 protease domain (mutant) – Dentue virus
2o1j – RvNSP4 diarrhea-inducing domain – Rotavirus
2gu0 – RvNS2
2ajj, 2ajm, 2ajn, 2ajo – NS5A membrane-anchor domain – bovine viral diarrhea virus – NMR
1fw5 – NSP1 membrane-binding domain – Semliki forest virus – NMR
1qol – NSP20A (mutant) - Foot-and-mouth disease virus
1nhu – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 – Hepatitis C virus
2gdt, 2hsx – SvNS1 (mutant) – Sars coronavirus – NMR
2jzd, 2jze, 2jzf, 2rnk – SvNS3 residues 527-651 – NMR
2kaf - SvNS3 residues 1473-1532 – NMR
2kys – SvNS7 – NMR
2l8k – NS7 residues 1454-1575 – NMR
3mtv – NS1 residues 181-383 – PRRS virus

Nonstructural protein binary complex

2xbm – DvNS5 methyltransferase domain + RNA
2hye – SvNSV + DNA damage-binding protein + cullin-4A + ring-box protein – Simian virus 5
2b5l - SvNSV + DNA damage-binding protein
1nhv – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 + inhibitor
1dxp, 1dy8, 1dy9 – HvNS4A + HvHelicase NS3
3phe – HvNS5B + quinolone derivative
3ub0 – NSP6 + NSP7 – Feline infectious peritonitis virus