NF-Y Transcription Factor Sandbox
From Proteopedia
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{{STRUCTURE_4awl| PDB=4awl | SCENE= }} | {{STRUCTURE_4awl| PDB=4awl | SCENE= }} | ||
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| + | === NF-Y Transcription Factor=== | ||
NF-Y transcription factor has three subunits composed of NF-YA, NF-YB, and NFY-C alpha helices. NF-YA subunit binds to both NF-YB and NF-YC subunits. The C terminal A2 helix of the NF-YA subunit inserts deep into the minor groove of DNA while the N terminal A1 helix of the NF-YA subunit interacts with NF-YB and NF-YC subunits. NF-YA A2 helix binds to the <scene name='56/566534/Ccaat_box/4'>CCAAT</scene> box and causes the minor groove to widen at the CCAAT box. An important residue in the catalytic site is <scene name='56/566534/Lysine_138/1'>Lys138</scene>. | NF-Y transcription factor has three subunits composed of NF-YA, NF-YB, and NFY-C alpha helices. NF-YA subunit binds to both NF-YB and NF-YC subunits. The C terminal A2 helix of the NF-YA subunit inserts deep into the minor groove of DNA while the N terminal A1 helix of the NF-YA subunit interacts with NF-YB and NF-YC subunits. NF-YA A2 helix binds to the <scene name='56/566534/Ccaat_box/4'>CCAAT</scene> box and causes the minor groove to widen at the CCAAT box. An important residue in the catalytic site is <scene name='56/566534/Lysine_138/1'>Lys138</scene>. | ||
Revision as of 15:12, 4 November 2013
NF-Y Transcription Factor
NF-Y transcription factor has three subunits composed of NF-YA, NF-YB, and NFY-C alpha helices. NF-YA subunit binds to both NF-YB and NF-YC subunits. The C terminal A2 helix of the NF-YA subunit inserts deep into the minor groove of DNA while the N terminal A1 helix of the NF-YA subunit interacts with NF-YB and NF-YC subunits. NF-YA A2 helix binds to the box and causes the minor groove to widen at the CCAAT box. An important residue in the catalytic site is .
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