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4ip8

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'''Unreleased structure'''
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{{STRUCTURE_4ip8| PDB=4ip8 | SCENE= }}
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===Structure of human serum amyloid A1===
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The entry 4ip8 is ON HOLD until Apr 15 2015
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==Disease==
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[[http://www.uniprot.org/uniprot/SAA1_HUMAN SAA1_HUMAN]] Secondary amyloidosis. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer.
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Authors: Lu, J., Sun, P.D
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==Function==
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[[http://www.uniprot.org/uniprot/SAA1_HUMAN SAA1_HUMAN]] Major acute phase reactant. Apolipoprotein of the HDL complex.
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Description: Structure of human serum amyloid A1
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==About this Structure==
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[[4ip8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IP8 OCA].
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[[Category: Lu, J.]]
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[[Category: Sun, P D]]
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[[Category: Four-helix bundle]]
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[[Category: Human serum]]
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[[Category: Main constituent of secondary amyloid]]
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[[Category: Protein binding]]
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[[Category: Secondary amyloid]]
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[[Category: Toll like receptor]]

Revision as of 09:31, 26 March 2014

Template:STRUCTURE 4ip8

Contents

Structure of human serum amyloid A1

Disease

[SAA1_HUMAN] Secondary amyloidosis. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer.

Function

[SAA1_HUMAN] Major acute phase reactant. Apolipoprotein of the HDL complex.

About this Structure

4ip8 is a 4 chain structure. Full crystallographic information is available from OCA.

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OCA

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