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4jo5
From Proteopedia
(Difference between revisions)
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| - | {{STRUCTURE_4jo5| PDB=4jo5 | SCENE= }} | ||
| - | ===CBM3a-L domain with flanking linkers from scaffoldin cipA of cellulosome of Clostridium thermocellum=== | ||
| - | {{ABSTRACT_PUBMED_23832198}} | ||
| - | == | + | ==CBM3a-L domain with flanking linkers from scaffoldin cipA of cellulosome of Clostridium thermocellum== |
| - | [[4jo5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum_ys Clostridium thermocellum ys]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JO5 OCA]. | + | <StructureSection load='4jo5' size='340' side='right' caption='[[4jo5]], [[Resolution|resolution]] 1.98Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4jo5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum_ys Clostridium thermocellum ys]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JO5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1MZ:1-METHYLIMIDAZOLE'>1MZ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nbc|1nbc]], [[1anu|1anu]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CIPA, YSBL_2973 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1094188 Clostridium thermocellum YS])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jo5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jo5 OCA], [http://pdbe.org/4jo5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jo5 RCSB], [http://www.ebi.ac.uk/pdbsum/4jo5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jo5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The cellulosome of the cellulolytic bacterium Clostridium thermocellum has a structural multi-modular protein called CipA (cellulosome-integrating protein A) that includes nine enzyme-binding cohesin modules and a family 3 cellulose-binding module (CBM3a). In the CipA protein, the CBM3a module is located between the second and third cohesin modules and is connected to them via proline/threonine-rich linkers. The structure of CBM3a with portions of the C- and N-terminal flanking linker regions, CBM3a-L, has been determined to a resolution of 1.98 A. The structure is a beta-sandwich with a structural Ca(2+) ion. The structure is consistent with the previously determined CipA CBM structure; however, the structured linker regions provide a deeper insight into the overall cellulosome structure and assembly. | ||
| - | + | Structure of a family 3a carbohydrate-binding module from the cellulosomal scaffoldin CipA of Clostridium thermocellum with flanking linkers: implications for cellulosome structure.,Yaniv O, Morag E, Borovok I, Bayer EA, Lamed R, Frolow F, Shimon LJ Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jul;69(Pt 7):733-7. doi:, 10.1107/S174430911301614X. Epub 2013 Jun 27. PMID:23832198<ref>PMID:23832198</ref> | |
| - | <ref | + | |
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 4jo5" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Clostridium thermocellum ys]] | [[Category: Clostridium thermocellum ys]] | ||
| - | [[Category: Bayer, E A | + | [[Category: Bayer, E A]] |
| - | [[Category: Frolow, F | + | [[Category: Frolow, F]] |
| - | [[Category: Lamed, R | + | [[Category: Lamed, R]] |
| - | [[Category: Morag, E | + | [[Category: Morag, E]] |
| - | [[Category: Shimon, L J.W | + | [[Category: Shimon, L J.W]] |
| - | [[Category: Yaniv, O | + | [[Category: Yaniv, O]] |
[[Category: Beta sandwich]] | [[Category: Beta sandwich]] | ||
[[Category: Cbm]] | [[Category: Cbm]] | ||
Revision as of 18:06, 4 August 2016
CBM3a-L domain with flanking linkers from scaffoldin cipA of cellulosome of Clostridium thermocellum
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