Interferon receptor
From Proteopedia
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<StructureSection load='3s9d' size='350' side='right' caption='Structure of interferon α/β receptor β chain ectodomain (green and yellow) complex with interferon-α 2 (grey and pink) and Cl- ion (green) (PDB entry [[3s9d]])' scene=''> | <StructureSection load='3s9d' size='350' side='right' caption='Structure of interferon α/β receptor β chain ectodomain (green and yellow) complex with interferon-α 2 (grey and pink) and Cl- ion (green) (PDB entry [[3s9d]])' scene=''> | ||
| - | '''Interferon receptor''' (IFNR) is a cell surface receptor which binds interferon. '''Interferon α/β receptor''' binds interferon-α and interferon-β. It is a heterodimer with subunits INFAR1 and INFAR2. '''Interferon γ receptor''' binds interferon-γ and is a heterodimer with subunits INFGR1 and INFGR2. '''Interferon δ receptor''' binds interferon-δ. | + | '''Interferon receptor''' (IFNR) is a cell surface receptor which binds interferon.<br /> |
| + | * '''Interferon α/β receptor''' binds interferon-α and interferon-β. It is a heterodimer with subunits INFAR1 and INFAR2.<br /> | ||
| + | * '''Interferon γ receptor''' binds interferon-γ and is a heterodimer with subunits INFGR1 and INFGR2.<br /> | ||
| + | * '''Interferon δ receptor''' binds interferon-δ. | ||
==3D structures of interferon receptor== | ==3D structures of interferon receptor== | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | + | ===Interferon α/β receptor=== | |
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[[3s98]] – hINFAR1 ectodomain – human <br /> | [[3s98]] – hINFAR1 ectodomain – human <br /> | ||
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[[3wcy]] – INFAR1 ectodomain + interferon-β - mouse <br /> | [[3wcy]] – INFAR1 ectodomain + interferon-β - mouse <br /> | ||
| - | + | ===Interferon γ receptor=== | |
[[1jrh]] – hINFGR1 N terminal (mutant) + antibody <br /> | [[1jrh]] – hINFGR1 N terminal (mutant) + antibody <br /> | ||
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[[4eq2]], [[4eq3]] – INFGR1 α chain - chicken <br /> | [[4eq2]], [[4eq3]] – INFGR1 α chain - chicken <br /> | ||
| - | + | ===Interferon δ receptor=== | |
[[3og4]], [[3og6]] – hINFDR1 extracellular domain + interleukin-29 <br /> | [[3og4]], [[3og6]] – hINFDR1 extracellular domain + interleukin-29 <br /> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 06:43, 19 August 2014
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