3umv
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3umv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryza_sativa_japonica_group Oryza sativa japonica group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UMV FirstGlance]. <br> | <table><tr><td colspan='2'>[[3umv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryza_sativa_japonica_group Oryza sativa japonica group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UMV FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=URE:UREA'>URE</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=URE:UREA'>URE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PHR, Os10g0167600, LOC_Os10g08580, OSJNAb0015J03.12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Oryza sativa Japonica Group])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PHR, Os10g0167600, LOC_Os10g08580, OSJNAb0015J03.12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39947 Oryza sativa Japonica Group])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxyribodipyrimidine_photo-lyase Deoxyribodipyrimidine photo-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.99.3 4.1.99.3] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxyribodipyrimidine_photo-lyase Deoxyribodipyrimidine photo-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.99.3 4.1.99.3] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3umv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3umv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3umv RCSB], [http://www.ebi.ac.uk/pdbsum/3umv PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3umv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3umv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3umv RCSB], [http://www.ebi.ac.uk/pdbsum/3umv PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PHR_ORYSJ PHR_ORYSJ]] Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutylpyrimidine dimers (CPDs), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. Required for plant survival in the presence of UV-B light. Not involved in the repair of (6-4) photoproducts.<ref>PMID:12764611</ref> <ref>PMID:15965242</ref> <ref>PMID:17895582</ref> <ref>PMID:17397507</ref> <ref>PMID:18235036</ref> <ref>PMID:20227927</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Eukaryotic Class II Cyclobutane Pyrimidine Dimer Photolyase Structure Reveals Basis for Improved Ultraviolet Tolerance in Plants.,Hitomi K, Arvai AS, Yamamoto J, Hitomi C, Teranishi M, Hirouchi T, Yamamoto K, Iwai S, Tainer JA, Hidema J, Getzoff ED J Biol Chem. 2012 Apr 6;287(15):12060-9. Epub 2011 Dec 14. PMID:22170053<ref>PMID:22170053</ref> | Eukaryotic Class II Cyclobutane Pyrimidine Dimer Photolyase Structure Reveals Basis for Improved Ultraviolet Tolerance in Plants.,Hitomi K, Arvai AS, Yamamoto J, Hitomi C, Teranishi M, Hirouchi T, Yamamoto K, Iwai S, Tainer JA, Hidema J, Getzoff ED J Biol Chem. 2012 Apr 6;287(15):12060-9. Epub 2011 Dec 14. PMID:22170053<ref>PMID:22170053</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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[[Category: Deoxyribodipyrimidine photo-lyase]] | [[Category: Deoxyribodipyrimidine photo-lyase]] | ||
[[Category: Oryza sativa japonica group]] | [[Category: Oryza sativa japonica group]] | ||
| - | [[Category: Arvai, A S | + | [[Category: Arvai, A S]] |
| - | [[Category: Getzoff, E D | + | [[Category: Getzoff, E D]] |
| - | [[Category: Hitomi, K | + | [[Category: Hitomi, K]] |
| - | [[Category: Tainer, J A | + | [[Category: Tainer, J A]] |
[[Category: Cpd cyclobutane pyrimidine dimer]] | [[Category: Cpd cyclobutane pyrimidine dimer]] | ||
[[Category: Dna repair]] | [[Category: Dna repair]] | ||
Revision as of 09:27, 25 December 2014
Eukaryotic Class II CPD photolyase structure reveals a basis for improved UV-tolerance in plants
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