Nonstructural protein

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{{STRUCTURE_3o9s| PDB=3o9s | SIZE=400| SCENE= |right|CAPTION=Nonstructural protein dimer [[3o9s]] }}
{{STRUCTURE_3o9s| PDB=3o9s | SIZE=400| SCENE= |right|CAPTION=Nonstructural protein dimer [[3o9s]] }}
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[[Nonstructural protein]] (NS) is a protein encoded by a virus which is not part of the viral particle. Pestivirus encode a NS at the N-terminal of their poluproteins (Npro). images at the left and at the right correspond to one representative NS, ''i.e.'' the crystal structure of Nonstructural protein from Influenza virus ([[3o9s]]). For homology model and multiple sequence alignment see<br />
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[[Nonstructural protein]] (NS) is a protein encoded by a virus which is not part of the viral particle. Pestivirus encode a NS at the N-terminal of their poluproteins (Npro). For homology model and multiple sequence alignment see<br />
*[[User:Michael Strong/H1N1/NS]]<br />
*[[User:Michael Strong/H1N1/NS]]<br />
*[[User:Michael Strong/H1N1/NS1/MSA]]<br />
*[[User:Michael Strong/H1N1/NS1/MSA]]<br />

Revision as of 08:04, 2 September 2014

Template:STRUCTURE 3o9s

Nonstructural protein (NS) is a protein encoded by a virus which is not part of the viral particle. Pestivirus encode a NS at the N-terminal of their poluproteins (Npro). For homology model and multiple sequence alignment see


3D Structures of Nonstructural protein

Updated on 02-September-2014

3o9q, 4opa, 4oph – IvNS1 (mutant) – Influenza virus
3o9r, 3o9s, 3o9t, 3o9u, 3f5t – IvNS1
3m8a, 2z0a, 1xeq, 1ail – IvNS1 RNA-binding domain
3p31 – IvNS1 C terminal effector domain
3p38, 3p39 – IvNS1 C terminal effector domain (mutant)
1ns1 - IvNS1 RNA-binding domain - NMR
3m5r, 2gx9 - IvNS1 effector domain
1pd3 – IvNS2 M1-binding domain
3l6p, 3lkw – DvNS2B/3 protease domain (mutant) – Dentue virus
2o1j – RvNSP4 diarrhea-inducing domain – Rotavirus
2gu0 – RvNS2
2ajj, 2ajm, 2ajn, 2ajo – NS5A membrane-anchor domain – bovine viral diarrhea virus – NMR
1fw5 – NSP1 membrane-binding domain – Semliki forest virus – NMR
1qol – NSP20A (mutant) - Foot-and-mouth disease virus
1nhu – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 – Hepatitis C virus
1r7c, 1r7d, 1r7e, 1r7f, 1r7g - HvNS5A membrane-anchor domain - NMR
2gdt, 2hsx – SvNS1 (mutant) – Sars coronavirus – NMR
2jzd, 2jze, 2jzf, 2rnk – SvNS3 residues 527-651 – NMR
2kaf - SvNS3 residues 1473-1532 – NMR
2kys – SvNS7 – NMR
2l8k – NS7 residues 1454-1575 – NMR
3mtv – NS1 residues 181-383 – PRRS virus
3zfn, 3zfo, 3zfq, 3zfp, 3zfr, 3zft, 3zfu – Npro (mutant) – Pestivirus

Nonstructural protein binary complex

2xbm – DvNS5 methyltransferase domain + RNA
2hye – SvNSV + DNA damage-binding protein + cullin-4A + ring-box protein – Simian virus 5
2b5l - SvNSV + DNA damage-binding protein
1nhv – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 + inhibitor
1dxp, 1dy8, 1dy9, 1w3c – HvNS4A + HvHelicase NS3
4a1t, 4a1x - HvNS4A + peptide inhibitor
3phe – HvNS5B + quinolone derivative
3ub0 – NSP6 + NSP7 – Feline infectious peritonitis virus
1knz – RvNSP34 N terminal + mRNA
1lj2 – RvNSP34 C terminal + eukaryotic protein synthesis initiation factor peptide

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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