Amino acid oxidase
From Proteopedia
(Difference between revisions)
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**[[1kif]] – pDAO – pig<br /> | **[[1kif]] – pDAO – pig<br /> | ||
| + | **[[3wgt]] – pDAO (mutant)<br /> | ||
**[[1c0l]] – RtDAO – ''Rhodosporidium toruloides''<br /> | **[[1c0l]] – RtDAO – ''Rhodosporidium toruloides''<br /> | ||
**[[2e48]] - hDAO – human<br /> | **[[2e48]] - hDAO – human<br /> | ||
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**[[2e49]] - hDAO + iminoserine <br /> | **[[2e49]] - hDAO + iminoserine <br /> | ||
**[[2e82]] - hDAO + imino-DOPA <br /> | **[[2e82]] - hDAO + imino-DOPA <br /> | ||
| - | **[[3cuk]], [[3w4i]], [[3w4j]], [[3w4k]], [[3znn]], [[3zno]], [[3znp]], [[3znq]] - hDAO + inhibitor <br /> | + | **[[3cuk]], [[3w4i]], [[3w4j]], [[3w4k]], [[3znn]], [[3zno]], [[3znp]], [[3znq]], [[4qfc]], [[4qfd]] - hDAO + inhibitor <br /> |
**[[3g3e]] - hDAO + hydroxyquinoline<br /> | **[[3g3e]] - hDAO + hydroxyquinoline<br /> | ||
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**[[1reo]] – HvLAO - Halys viper <br /> | **[[1reo]] – HvLAO - Halys viper <br /> | ||
**[[3kve]] – LAO + Zn – ''Vipera ammodytes''<br /> | **[[3kve]] – LAO + Zn – ''Vipera ammodytes''<br /> | ||
| + | **[[4cnj]], [[4cnk]] – LAO + FAD – ''Streptococcus oligofermentans''<br /> | ||
*L-amino acid oxidase complex | *L-amino acid oxidase complex | ||
Revision as of 12:00, 28 January 2015
Template:STRUCTURE 2jb1 Amino acid oxidase catalyzes the oxidation of amino acids to the keto acid producing ammonia and hydrogen peroxide. These enzymes oxidize D-amino acids (DAO) and L-amino acids (LAO). The LAO oxidation products are 2-oxo acid, ammonia and hydrogen peroxide. LAO is widely found in snake venom. DAOs oxidize neutral and basic D-amino acids. Some DAOs are used in cancer therapy as inducers of oxidative stress and apoptosis. DAO and LAO use FAD as a cofactor.
3D structures of amino acid oxidase
Updated on 28-January-2015
