4mr0
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mr0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mr0 RCSB], [http://www.ebi.ac.uk/pdbsum/4mr0 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mr0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mr0 RCSB], [http://www.ebi.ac.uk/pdbsum/4mr0 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PFBA_STRR6 PFBA_STRR6]] Acts as a fibronectin-dependent adhesin and invasin. Binds host (in this case human) fibronectin, plasmin, plasminogen, and human serum albumin. Where the bacteria adhere to human cells there is major recruitment of microvilli which seem to fuse to cover the streptococcal chains. Antibodies to this protein reduce bacterial growth in human blood. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 19:48, 25 December 2014
Crystal structure of PfbA, a surface adhesin of Streptococcus pneumoniae
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