4qi9
From Proteopedia
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==Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate== | ==Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate== | ||
<StructureSection load='4qi9' size='340' side='right' caption='[[4qi9]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='4qi9' size='340' side='right' caption='[[4qi9]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q1h|3q1h]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q1h|3q1h]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qi9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qi9 RCSB], [http://www.ebi.ac.uk/pdbsum/4qi9 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qi9 OCA], [http://pdbe.org/4qi9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qi9 RCSB], [http://www.ebi.ac.uk/pdbsum/4qi9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qi9 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/Q7CG83_YERPE Q7CG83_YERPE]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194] | [[http://www.uniprot.org/uniprot/Q7CG83_YERPE Q7CG83_YERPE]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194] | ||
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| + | ==See Also== | ||
| + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 00:42, 5 August 2016
Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate
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Categories: Dihydrofolate reductase | Anderson, W F | Structural genomic | Joachimiak, A | Kim, Y | Makowska-Grzyska, M | Maltseva, N | Mulligan, R | Shatsman, S | Alpha beta fold | Csgid | National institute of allergy and infectious disease | Niaid | Oxidoreductase-oxidoreductase inhibitor complex
