Sandbox jmu01
From Proteopedia
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This article describes the crystallization of HIV Protease with various inhibitors including the K13 inhibitor shown in this structure. <ref>http://dx.doi.org/10.1016/j.chembiol.2013.07.014</ref> | This article describes the crystallization of HIV Protease with various inhibitors including the K13 inhibitor shown in this structure. <ref>http://dx.doi.org/10.1016/j.chembiol.2013.07.014</ref> | ||
| - | + | Here I have highlighted key nonpolar residues in the <scene name='71/713483/Active_site_zoom/1'>active site</scene> that make van der Waals interactions with K13. The inhibitor has a longer hydrophobic region so it binds tighter here. | |
Revision as of 18:59, 5 October 2015
HIV Protease Inhibitor
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