Calpain
From Proteopedia
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* '''CAP8''' and '''CAP9''' are involved in the mucosal defense against stress-induced gastropathies.<br /> | * '''CAP8''' and '''CAP9''' are involved in the mucosal defense against stress-induced gastropathies.<br /> | ||
* '''CAP9''' has been identified as the tumor suppressor for gastric cancer.<br /> | * '''CAP9''' has been identified as the tumor suppressor for gastric cancer.<br /> | ||
| - | * '''CAP13''' is expressed in testis and lungs. | + | * '''CAP13''' is expressed in testis and lungs.<ref>PMID:12843408</ref> |
==Disease== | ==Disease== | ||
Revision as of 13:32, 18 November 2015
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3D structures of calpain
Updated on 18-November-2015
References
- ↑ Goll DE, Thompson VF, Li H, Wei W, Cong J. The calpain system. Physiol Rev. 2003 Jul;83(3):731-801. PMID:12843408 doi:http://dx.doi.org/10.1152/physrev.00029.2002
- ↑ Moldoveanu T, Hosfield CM, Lim D, Elce JS, Jia Z, Davies PL. A Ca(2+) switch aligns the active site of calpain. Cell. 2002 Mar 8;108(5):649-60. PMID:11893336
- ↑ Li Q, Hanzlik RP, Weaver RF, Schonbrunn E. Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core. Biochemistry. 2006 Jan 24;45(3):701-8. PMID:16411745 doi:http://dx.doi.org/10.1021/bi052077b
