2vi0

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==LICHENASE CTLIC26 IN COMPLEX WITH A THIO-OLIGOSACCHARIDE==
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==Lichenase CtLic26 in complex with a thio-oligosaccharide==
<StructureSection load='2vi0' size='340' side='right' caption='[[2vi0]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
<StructureSection load='2vi0' size='340' side='right' caption='[[2vi0]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vi0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ruminiclostridium_thermocellum Ruminiclostridium thermocellum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VI0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VI0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2vi0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"ruminiclostridium_thermocellum"_yutin_and_galperin_2013 "ruminiclostridium thermocellum" yutin and galperin 2013]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VI0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VI0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=VAM:METHYL+4-O-(4-THIO-BETA-D-GLUCOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE'>VAM</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=VAM:METHYL+4-O-(4-THIO-BETA-D-GLUCOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE'>VAM</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1v0a|1v0a]], [[2bv9|2bv9]], [[2bvd|2bvd]], [[2cit|2cit]], [[2v3g|2v3g]], [[2cip|2cip]], [[2v80|2v80]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1v0a|1v0a]], [[2bv9|2bv9]], [[2bvd|2bvd]], [[2cit|2cit]], [[2v3g|2v3g]], [[2cip|2cip]], [[2v80|2v80]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">celH, Cthe_1472 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1515 "Ruminiclostridium thermocellum" Yutin and Galperin 2013])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vi0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vi0 OCA], [http://pdbe.org/2vi0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vi0 RCSB], [http://www.ebi.ac.uk/pdbsum/2vi0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vi0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vi0 OCA], [http://pdbe.org/2vi0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vi0 RCSB], [http://www.ebi.ac.uk/pdbsum/2vi0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vi0 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GUNH_CLOTH GUNH_CLOTH]] This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vi/2vi0_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vi/2vi0_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ruminiclostridium thermocellum yutin and galperin 2013]]
[[Category: Cellulase]]
[[Category: Cellulase]]
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[[Category: Ruminiclostridium thermocellum]]
 
[[Category: Davies, G J]]
[[Category: Davies, G J]]
[[Category: Ducros, V M]]
[[Category: Ducros, V M]]

Revision as of 20:01, 19 September 2018

Lichenase CtLic26 in complex with a thio-oligosaccharide

2vi0, resolution 1.51Å

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