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Glucagon
From Proteopedia
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== Function == | == Function == | ||
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Glucagon is injected in cases of severe glycemia<ref>PMID:15793249</ref>. Overdose of β blockers is treated with GLCas well as cases of Epinephrin-resistant low blood pressure. Pancreatic tumors may cause high levels of GLC. | Glucagon is injected in cases of severe glycemia<ref>PMID:15793249</ref>. Overdose of β blockers is treated with GLCas well as cases of Epinephrin-resistant low blood pressure. Pancreatic tumors may cause high levels of GLC. | ||
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== 3D Structures of glucagon == | == 3D Structures of glucagon == | ||
Revision as of 09:14, 24 May 2017
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3D Structures of glucagon
Updated on 24-May-2017
2g49 – hGLC preprotein residues 53-81+ insulin-degrading enzyme – human
1kx6, 2m5p, 2m5q – hGLC - NMR
1nau – hGLC (mutant) – NMR
1bh0 - hGLC (mutant)
1gcn - hGLC
References
- ↑ Ramnanan CJ, Edgerton DS, Kraft G, Cherrington AD. Physiologic action of glucagon on liver glucose metabolism. Diabetes Obes Metab. 2011 Oct;13 Suppl 1:118-25. doi:, 10.1111/j.1463-1326.2011.01454.x. PMID:21824265 doi:http://dx.doi.org/10.1111/j.1463-1326.2011.01454.x
- ↑ Heptulla RA, Rodriguez LM, Bomgaars L, Haymond MW. The role of amylin and glucagon in the dampening of glycemic excursions in children with type 1 diabetes. Diabetes. 2005 Apr;54(4):1100-7. PMID:15793249
