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Methyl CpG binding protein

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**[[1ig4]] – hMBD1 MBD domain + DNA – human – NMR<br />
**[[1ig4]] – hMBD1 MBD domain + DNA – human – NMR<br />
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**[[1d9n]] - hMBD1 MBD domain – NMR
+
**[[1d9n]] - hMBD1 MBD domain – NMR<br />
 +
**[[4d4w]] - hMBD1 CXXC1 domain – NMR<br />
*Methyl CpG binding protein 2 (MBD2)
*Methyl CpG binding protein 2 (MBD2)

Revision as of 09:22, 24 April 2016

Structure of mouse MBD4 glycosylate domain complex with DNA containing mismatch, ethylene glycol and Ni+2 ion (green) (PDB code 4evv).

Drag the structure with the mouse to rotate

3D structures of methyl CpG binding protein

Updated on 24-April-2016

References

  1. ↑ Wade PA. Methyl CpG-binding proteins and transcriptional repression. Bioessays. 2001 Dec;23(12):1131-7. PMID:11746232 doi:http://dx.doi.org/10.1002/bies.10008
  2. ↑ Van den Veyver IB, Zoghbi HY. Mutations in the gene encoding methyl-CpG-binding protein 2 cause Rett syndrome. Brain Dev. 2001 Dec;23 Suppl 1:S147-51. PMID:11738862
  3. ↑ Hashimoto H, Zhang X, Cheng X. Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation. Nucleic Acids Res. 2012 Jun 27. PMID:22740654 doi:10.1093/nar/gks628

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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