5itv
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Bacillus subtilis BacC Dihydroanticapsin 7-dehydrogenase in complex with NADH== | |
| - | + | <StructureSection load='5itv' size='340' side='right' caption='[[5itv]], [[Resolution|resolution]] 2.26Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5itv]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ITV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ITV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5itw|5itw]]</td></tr> |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroanticapsin_7-dehydrogenase Dihydroanticapsin 7-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.385 1.1.1.385] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5itv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5itv OCA], [http://pdbe.org/5itv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5itv RCSB], [http://www.ebi.ac.uk/pdbsum/5itv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5itv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BACC_BACSU BACC_BACSU]] Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the dehydrogenation of the C7-hydroxyl group in the 4S-tetrahydrotyrosine (4S-H4Tyr) to yield anticapsin (epoxycyclohexanonyl-Ala). It is not able to oxidize the 4R-H4Tyr diastereomer and the dihydrobacilysin dipeptide (L-Ala-4S-H4Tyr dipeptide).<ref>PMID:15609023</ref> <ref>PMID:23317005</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Dihydroanticapsin 7-dehydrogenase]] | ||
[[Category: Balaram, H]] | [[Category: Balaram, H]] | ||
[[Category: Gopal, B]] | [[Category: Gopal, B]] | ||
| - | [[Category: Row, T | + | [[Category: Perinbam, K]] |
| + | [[Category: Row, T N.G]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Rossmann fold]] | ||
| + | [[Category: Short-chain dehydrogenases/reductase]] | ||
Revision as of 01:35, 11 March 2017
Crystal structure of Bacillus subtilis BacC Dihydroanticapsin 7-dehydrogenase in complex with NADH
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