Methyl CpG binding protein
From Proteopedia
(Difference between revisions)
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**[[2l2l]] - hMBD2 coiled-coil domain + transcriptional repressor p66-α coiled-coil domain – NMR<br /> | **[[2l2l]] - hMBD2 coiled-coil domain + transcriptional repressor p66-α coiled-coil domain – NMR<br /> | ||
| + | **[[5bt2]] – hMBD2 MBD + methylated DNA <br /> | ||
**[[2ky8]] – cMBD2 MBD domain + DNA containing cytidine and uridine derivatives - NMR - chicken<br /> | **[[2ky8]] – cMBD2 MBD domain + DNA containing cytidine and uridine derivatives - NMR - chicken<br /> | ||
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**[[3vxv]], [[3vxx]], [[3vyb]], [[3vyq]] – mMBD4 MBD + DNA containing cytidine derivative<br /> | **[[3vxv]], [[3vxx]], [[3vyb]], [[3vyq]] – mMBD4 MBD + DNA containing cytidine derivative<br /> | ||
**[[4lg7]], [[2moe]] – hMBD4 MBD + DNA containing cytidine derivative<br /> | **[[4lg7]], [[2moe]] – hMBD4 MBD + DNA containing cytidine derivative<br /> | ||
| + | **[[5chz]] – hMBD4 MBD + DNA containing mismatch<br /> | ||
**[[4ofa]], [[4ofe]], [[4ofh]] – hMBD4 MBD (mutant) + DNA containing mismatch<br /> | **[[4ofa]], [[4ofe]], [[4ofh]] – hMBD4 MBD (mutant) + DNA containing mismatch<br /> | ||
Revision as of 08:57, 20 July 2017
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3D structures of methyl CpG binding protein
Updated on 20-July-2017
References
- ↑ Wade PA. Methyl CpG-binding proteins and transcriptional repression. Bioessays. 2001 Dec;23(12):1131-7. PMID:11746232 doi:http://dx.doi.org/10.1002/bies.10008
- ↑ Van den Veyver IB, Zoghbi HY. Mutations in the gene encoding methyl-CpG-binding protein 2 cause Rett syndrome. Brain Dev. 2001 Dec;23 Suppl 1:S147-51. PMID:11738862
- ↑ Hashimoto H, Zhang X, Cheng X. Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation. Nucleic Acids Res. 2012 Jun 27. PMID:22740654 doi:10.1093/nar/gks628
